Advertisement

Obesity Surgery

, Volume 29, Issue 6, pp 1851–1857 | Cite as

Weight Loss, Remission of Comorbidities, and Quality of Life After Bariatric Surgery in Young Adult Patients

  • M. I. CooimanEmail author
  • E. O. Aarts
  • I. M. C. Janssen
  • E. J. Hazebroek
  • F. J. Berends
Original Contributions

Abstract

Introduction

One of the current criteria for bariatric surgery is to be of an age between 18 and 65 years. In all the available literature, there is a lack of studies focusing on the results of bariatric surgery in younger patient. This could be of great interest because the weight loss response can be altered by differences in metabolism or compliance rate. In recent years, a high amount of patients between 18 and 25 years of age have undergone bariatric surgery in our center, and it is our aim to evaluate the weight loss results in this youngest patient group.

Methods

All preoperative and perioperative data from patients aged 18–25 and 35–55 years (control group) were collected retrospectively. Bariatric procedures took place between 2011 and 2014. Follow-up data were gathered prospectively by collecting (laboratory) measurements and questionnaires.

Results

In total, 103 young adults (mean age 22.5) were matched to 103 adult control patients (mean age 42.6) on BMI and date of surgery. Of the young adults’ group, 75 patients underwent a Roux-en-Y gastric bypass (RYGB) compared with 80 patients in the control group. Three years after RYGB, mean %total body weight loss (%TBWL) was 34 (± 9) and 30.3 (± 9) (p = 0.03), respectively.

Conclusion

Bariatric surgery is effective in young adults, and results after RYGB are even better compared with age groups in which bariatric surgery is most often performed. The high remission rate of comorbidities shows the importance of effective treatment options at a young age and preventing damaging effects in the long term.

Keywords

Bariatric surgery Obesity Young adults Gastric bypass Sleeve gastrectomy 

Notes

Compliance with Ethical Standards

This study was approved by the national ethical committee and the local institutional review board. Written informed consent was obtained from all participants.

Conflict of Interest

The authors declare that they have no conflict of interest.

Supplementary material

11695_2019_3781_MOESM1_ESM.docx (20 kb)
ESM 1 (DOCX 19 kb).

References

  1. 1.
    Baker JL, Olsen LW, Sorensen TIA. Childhood body-mass index and the risk of coronary heart disease in adulthood. N Engl J Med. 2007;357(23):2329–37.CrossRefGoogle Scholar
  2. 2.
    Dam van RM, Willnett WC, Manson JE, et al. The relationship between overweight in adolescence and premature death in women. Ann Intern Med. 2006;145:91–7.CrossRefGoogle Scholar
  3. 3.
    Crocker MK, Yavoniski JA. Pediatric obesity: etiology and treatment. Pediatr Clin N Am. 2011;58:1217–40.CrossRefGoogle Scholar
  4. 4.
    Pavkov ME, Bennet PH, Knowler WC, et al. Effect of youth-onset type 2 diabetes mellitus on incidence of end-stage renal disease and mortality in young and middle-aged Pima Indians. JAMA. 2006;296(4):421–6.CrossRefGoogle Scholar
  5. 5.
    Freedman DS, Zuguo M, Srinivasan SR, et al. Cardiovascular risk factors and excess adiposity among overweight children and adolescents: the Bogalusa Heart Study. J Pediatr. 2007;150:12–7.CrossRefGoogle Scholar
  6. 6.
    Cazzo E, Gestic MA, Utrini MP, et al. Bariatric surgery in the elderly: a narrative review. Rev Assoc Med Bras. 2017;63(9):787–92.CrossRefGoogle Scholar
  7. 7.
    Roux le CW, Heneghan HM. Bariatric surgery for obesity. Med Clin N Am. 2018;102:165–82.CrossRefGoogle Scholar
  8. 8.
    Sjostrom L. Review of the key results from the Swedish Obese Subjects (SOS) trial – a prospective controlled intervention study of bariatric surgery. J Intern Med. 2013;273:219–34.CrossRefGoogle Scholar
  9. 9.
    Cooper TC, Simmons EB, Webb K, et al. Trends in weight regain following Roux-en-Y gastric bypass (RYGB) bariatric surgery. Obes Surg. 2015;25:1474–81.  https://doi.org/10.1007/s11695-014-1560-z.CrossRefPubMedGoogle Scholar
  10. 10.
    Kaska L, Sledzinski T, Chomiczewska A, et al. Improved glucose metabolism following bariatric surgery is associated with increased circulating bile acid concentrations and remodeling of the gut microbiome. World J Gastroenterol. 2016;22(39):8698–719.CrossRefGoogle Scholar
  11. 11.
    Felsenreich DM, Ladinig LM, Beckerhinn P, et al. Update: 10 years of sleeve gastrectomy – the first 103 patients. Obes Surg. 2018;28:3586–94.  https://doi.org/10.1007/s11695-018-3399-1.CrossRefPubMedPubMedCentralGoogle Scholar
  12. 12.
    Thereaux J, Lesuffleur T, Czernichow S, et al. Association between bariatric surgery and rates of continuation, discontinuation or initiation of antidiabetic treatment 6 years later. JAMA. 2018;  https://doi.org/10.1001/jamasurg.2017.6163.CrossRefGoogle Scholar
  13. 13.
    Shah K, Nergard BJ, Frazier KS, et al. Long-term effects of laparoscopic Roux-en-Y gastric bypass on metabolic syndrome in patients with morbid obesity. Surg Obes Relat Dis. 2016;12(8):1449–56.CrossRefGoogle Scholar
  14. 14.
    Ikramuddin S, Korner J, Lee W-J, et al. Lifestyle intervention and medical management with vs without Roux-en-Y gastric bypass and control of hemoglobin A1c, LDL cholesterol, and systolic blood pressure at 5 years in the Diabetes Surgery Study. JAMA. 2018;319(3):266–78.CrossRefGoogle Scholar
  15. 15.
    Benaiges D, Sague M, Flores-Le Roux JA, et al. Predictors of hypertension remission and recurrence after bariatric surgery. Am J Hypertens. 2015;29(5):653–9.CrossRefGoogle Scholar
  16. 16.
    Kolotkin RL, Andersen JR. A systematic review of reviews: exploring the relationship between obesity, weight loss and health-related quality of life. Clin Obes. 2017;7:273–89.CrossRefGoogle Scholar
  17. 17.
    Livhits M, Mercado C, Yermilov I, et al. Behavioral factors associated with successful weight loss after gastric bypass. Am Surg. 2010;76(10):1139–42.PubMedGoogle Scholar
  18. 18.
    Jong de MMC, Hinnen C. Bariatric surgery in young adults: a multicenter study into weight loss, dietary adherence and quality of life. SOARD. 2017;13:1204–11.Google Scholar
  19. 19.
    Bailly L, Schiavo L, Sebastianelli L, et al. Anemia and bariatric surgery: results of a national French survey of administrative data of 306,298 consecutive patients between 2008 and 2016, Obes Surg. 2018;  https://doi.org/10.1007/s11695-018-3143.x.
  20. 20.
    Lupoli R, Lembo E, Saldalamcchia G, et al. Bariatric surgery and long-term nutritional issues. World J Diabetes. 2017;8(11):464–74.CrossRefGoogle Scholar
  21. 21.
    McVay MA, Friedman KE, Applegate KL, et al. Patients predictors of follow-up care attendance in Roux-en-Y gastric bypass patients. SOARD. 2013;9:956–62.Google Scholar

Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2019

Authors and Affiliations

  1. 1.Department of Bariatric SurgeryRijnstate Hospital/Vitalys ClinicsArnhemThe Netherlands

Personalised recommendations