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Obesity Surgery

, Volume 28, Issue 12, pp 3958–3964 | Cite as

Prevalence and Factors Associated with Helicobacter Pylori in Patients Undergoing Bariatric Surgery: the SOON Cohort

  • Sandrine Coumes
  • Bruno Froissart
  • Nelly Wion
  • Fabian Reche
  • Catherine Arvieux
  • Anne-Laure Borel
Original Contributions

Abstract

Purpose

Helicobacter Pylori (HP) infection is systematically screened for before carrying out bariatric surgery. Criteria to determine “at risk” patients and avoid systematic screening are lacking. We evaluated the prevalence of HP infection and associated predictive factors in a population of patients with class II and III obesity volunteering for bariatric surgery.

Materials and Methods

Observational, cross-sectional study of patients included in the severe obesity outcome network (SOON) cohort. All patients underwent HP screening. The relationship between plasma metabolic parameters and vitamin levels, medical history and socio-economic parameters, and HP infection was analyzed.

Results

Data from 201 patients, median age 43 years [IQR 35; 52] (81% female) were analyzed. Forty-four patients (22%) were infected with HP and successfully treated, most with a single course of treatment, either combined antibiotics or Pylera®. HP infection was associated with social precariousness as defined by the French “Evaluation de la Précarité et des Inégalités de santé dans les Centres d’Examens de Santé” (EPICES) score (Evaluation of Poverty and Health Inequalities in Health-Assessment Centers) (OR, 1.027; 95% CI, 1.008–1.046; p < 0.004) and with higher levels of vitamin B12 (OR, 1.004; 95% CI, 1.001–1.007; p < 0.007).

Conclusion

The prevalence of HP infection was 22% and was associated with social precariousness. Plasma glucose/insulin and lipid/lipoprotein profiles, liver enzymes or vitamin deficiencies were not associated with HP infection. The number of characteristics associated with HP infection was insufficient to define patients who do not require HP screening before bariatric surgery.

Keywords

Helicobacter pylori Bariatric surgery Prevalence 

Notes

Acknowledgements

The authors thank Matthieu Lesgoirres, clinical research assistant, for his help with the clinical research in the SOON cohort. We thank Johanna Robertson, native English speaker, for English language editing.

Funding

“Fond Agir pour les maladies chroniques” and “Agence Régionale de la Santé Auvergne Rhône-Alpes ».

Compliance with Ethical Standards

Human and Animal Rights

All patients signed informed consent for their inclusion in the SOON cohort and the study was approved by our local ethics committee. The SOON cohort is registered on ClinicalTrials.gov (NCT02264431).

Informed Consent

Informed consent was obtained from all individual participants included in the study.

Conflict of Interest

The authors declare that they have no conflict of interest.

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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Nutrition DepartmentGrenoble Alpes University HospitalGrenobleFrance
  2. 2.Hepato-Gastro-Enterology Outpatient Private Clinic “Les Cèdres”GrenobleFrance
  3. 3.Digestive Surgery DepartmentGrenoble Alpes University HospitalGrenobleFrance
  4. 4.Hypoxia-Pathophysiology (HP2) Laboratory, INSERM U1042Grenoble-Alpes UniversityGrenobleFrance

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