Obesity Surgery

, Volume 29, Issue 2, pp 645–646 | Cite as

Invited Response Letter: Our Experience Regarding the Association Between Gastrointestinal Stromal Tumor and Bariatric Surgery. A Response to a Letter “Gastrointestinal Stromal Tumor After Laparoscopic Sleeve Gastrectomy: Be Awake Before, During, and After a Bariatric Procedure”

  • Sonja ChiappettaEmail author
  • Christine Stier
  • Rudolf A. Weiner
  • Norbert Runkel
Letter to Editor/LED Reply

Invited Response Letter:

We are grateful to the authors for the presentation of another 12 cases of incidental gastrointestinal stromal tumors (GISTs) during bariatric surgery which substantially expands the current knowledge [1]. We appreciate the opportunity to respond.

The published patients were slightly older (mean age 53.8 years) than our 26 cases (mean age 50.5 years) reported earlier in this journal, but still in the same range [2, 3]. The localization of the tumors in the gastric fundus was somewhat higher than in our population (91.1% vs. 77.7%, respectively), although both, gastric corpus and fundus, are in accordance with the anatomical distribution of interstitial cells of Cajal as origin of the tumor formations [4].

Most gastric GISTs are discovered during the operation rather than before. This may have a substantial impact and often generates the need for a prompt intraoperative decision and consecutive adaption of the bariatric strategy to the specific situation. In our...


Compliance with Ethical Standards

Conflict of Interest

The authors declare that they have no conflicts of interest.


  1. 1.
    Letter to the Editor. Obesity Surgery.Google Scholar
  2. 2.
    Chiappetta S, Theodoridou S, Stier C, et al. Incidental finding of GIST during obesity surgery. Obes Surg. 2015;25(3):579–83.CrossRefGoogle Scholar
  3. 3.
    Chiappetta S, Stier C, Weiner RA. Invited response letter: “Gastrointestinal stromal tumor after laparoscopic sleeve gastrectomy: be awake before, during, and after a bariatric procedure”. Obes Surg. 2018;28(7):2048–9.CrossRefGoogle Scholar
  4. 4.
    Yun HY, Sung R, Kim YC, et al. Regional distribution of interstitial cells of Cajal (ICC) in human stomach. Korean J Physiol Pharmacol. 2010;14(5):317–24.CrossRefGoogle Scholar
  5. 5.
    Angrisani L, Santonicola A, Iovino P, et al. IFSO Worldwide Survey 2016: primary, endoluminal, and revisional procedures. Obes Surg. 2018;28:3783–94.CrossRefGoogle Scholar
  6. 6.
    Bhaskaran K, Douglas I, Forbes H, et al. Body-mass index and risk of 22 specific cancers: a population-based cohort study of 5.24 million UK adults. Lancet. 2014;384(9945):755–65.CrossRefGoogle Scholar
  7. 7.
    Fernandez JA et al. Additional malignancies in patients with gastrointestinal stromal tumors (GIST): incidence, pathology and prognosis according to a time of occurrence-based classification. Clin Transl Oncol. 2018.
  8. 8.
    Casali PG et al. Gastrointestinal stromal tumours: ESMO-EURACAN clinical practice guidelines for diagnosis, treatment and follow-up. Ann Oncol. 2018;29(Supplement_4):iv267.CrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Department of Obesity and Metabolic SurgerySana Klinikum OffenbachOffenbach am MainGermany

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