Rhabdomyolysis After Sleeve Gastrectomy: Increase in Muscle Enzymes Does Not Predict Fatal Outcome
- 102 Downloads
Rhabdomyolysis (RML) is a clinical and biochemical syndrome caused by destruction of skeletal muscles and constitutes a complication of bariatric surgery, with an incidence near to 22%. It is accompanied by increase in serum of intracellular enzymes. Laboratory data as predictive of prognosis have been evaluated by some authors. We report a case of RML after a sleeve gastrectomy, with good prognosis despite a very extensive muscle damage and very high seric and urinary peaks of intracellular enzymes.
We describe a 34-years-old super-obese male (body mass index, 54.3 kg/m2) who underwent to laparoscopic sleeve gastrectomy. After 24 h, patient complained of pain in gluteal region, oliguria, and high levels of creatine phosphokinase that reached to 58,395 IU/l. Acute renal failure related to RML was diagnosed. Dialysis was not necessary. Ambulatorial control of renal function after dimission did not reveal a permanent damage.
RML is a biochemical syndrome recently associated with bariatric surgery. Early diagnosis is ever necessary. Laboratory data represent markers for diagnosis and prognostic indicator of renal failure. There is no clear relation between seric levels of intracellular enzymes and irreversible renal damage and RML-related mortality.
KeywordsRhabdomyolysis Sleeve gastrectomy Creatine kinase Bariatric surgery Obesity
- 2.Gabow PA, Kaehny WD, Kelleher SP. The spectrum of rhabdomyolisis. Medicine (Baltimore) 1982;61:141–52.Google Scholar
- 3.Singh D, Chander V, Chopra K. Rhabdomyolysis. Exp Clin Pharmacol 2005;27:39–48.Google Scholar
- 4.Criddle LM. Rhabdomyolysis. Pathophysiology, recognition, and management. Crit Care Nurs 2003;23:14–22, 24–6, 28.Google Scholar
- 12.Fernandex-Funez A, de Tomas E, Alamillo A, et al. Nontraumatic rhabdomyolysis: its etiology and the predictive factors of acute kidney failure. Med Clin 1995;105:412–5.Google Scholar