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Effects of Heat Treatment on Microstructure, Mechanical Properties, Corrosion Resistance and Cytotoxicity of ZM21 Magnesium Alloy as Biomaterials

  • Dayue Jiang
  • Yilong Dai
  • Yu Zhang
  • Yang Yan
  • Jiaji Ma
  • Ding Li
  • Kun YuEmail author
Article
  • 69 Downloads

Abstract

The effects of heat treatment on microstructure, mechanical properties, corrosion resistance and cytotoxicity of extruded Mg-2Zn-1Mn (wt.%) alloy were investigated for biomedical application in this study. The extruded alloy was T4 treated at 510 °C for 4 h and T5 treated at 200 °C for 16 h separately. The extruded Mg-Zn-Mn alloy mainly consists of MgxMny phases. After T4 treatment, the amount of MgxMny phases decreases and average grain size rises from 8 to 24 μm. After T5 treatment, Mg7Zn3 phase newly precipitates along the grain boundaries and the size of grain remains similar. Compared with the T4-treated samples, the extruded and T5-treated samples exhibit higher mechanical properties. The T5-treated samples have an ultimate tensile stress of 273 MPa and an elongation of 19.7%. On the other hand, T4-treated samples present higher corrosion resistance in electrochemical tests. The degradation rates of extruded, T4-treated and T5-treated samples are 0.44 mm/year, 0.48 mm/year and 0.50 mm/year, respectively, in Ringer’s solution at 37 ± 0.2 °C. In addition, T4-treated alloy does not induce toxicity to the L-929 cells in in vitro cytotoxicity test.

Keywords

biomaterial corrosion properties cytotoxicity heat treatment magnesium 

Notes

Acknowledgments

This work was supported by the Natural Science Foundation of Hunan Province of China (2018JJ2506). The authors acknowledge the Project (2017GK2120) supported by the Key Research and Development Program of Hunan Province. This work also received financial support of the Natural Science Foundation of Shandong Province of China (ZR2017MEM005) and 2015 ShanDong province project of outstanding subject talent group.

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Copyright information

© ASM International 2018

Authors and Affiliations

  • Dayue Jiang
    • 1
  • Yilong Dai
    • 1
  • Yu Zhang
    • 1
  • Yang Yan
    • 1
  • Jiaji Ma
    • 1
  • Ding Li
    • 2
  • Kun Yu
    • 1
    Email author
  1. 1.School of Materials Science and EngineeringCentral South UniversityChangshaChina
  2. 2.The Second Xiangya Hospital of Central South UniversityChangshaChina

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