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Mechanical Integrity of Biodegradable Mg–HA Composite During In Vitro Exposure

  • Anshu Dubey
  • Satish Jaiswal
  • Debrupa LahiriEmail author
Article
  • 23 Downloads

Abstract

Biodegradable metals are being frequently explored as a very potential replacement for bone implant and fixing accessories, owing to their superior mechanical and biological properties. In connection to this, biodegradable magnesium (Mg) and its alloys exhibit good biocompatibility for orthopedic applications. Nevertheless, the use of these biodegradable materials has been restricted due to their fast degradation rate in the physiological environment, even before the new tissue is adequately generated. So, it becomes necessary to bring down their corrosion rate to retain their mechanical integrity until the bone properly heals. A solution to this problem is found in hydroxyapatite (HA)-reinforced Mg-based composites. However, it is important to understand the mechanical behavior of these materials, after exposure to body environment. In this study, HA-reinforced composites of Mg-based (Mg-3Zn) matrix are evaluated for their mechanical integrity in simulated in vitro condition. Addition of 5 wt.% HA decreased the corrosion rate of Mg-3Zn, which in turn maintained the mechanical integrity of the structures even after 14 days of immersion. Mg-3Zn and Mg-3Zn-5HA composites have retained ~ 34 and 66% of ultimate compressive strength after 3 days of immersion. All these studies together establish the effect of HA on mechanical integrity of Mg-based composites in orthopedic application.

Keywords

hydroxyapatite in vitro immersion magnesium mechanical integrity orthopedic fixture accessories 

Notes

Acknowledgments

The authors are thankful to all the laboratory staff of Department of Metallurgical and Materials Engineering Department, IIT, Roorkee, for their facilities. DL acknowledges the financial support from funding by Department of Science and Technology, India (SB/SO/HS/138/2013). Authors are also grateful to Mr. Manoj Kumar R and Ms. Ankita Bisht for their technical support at the time of experiment.

Supplementary material

11665_2018_3778_MOESM1_ESM.docx (74 kb)
Supplementary material 1 (DOCX 74 kb)

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Copyright information

© ASM International 2019

Authors and Affiliations

  1. 1.Biomaterials and Multiscale Mechanics Lab, Department of Metallurgical and Materials EngineeringIndian Institute of Technology RoorkeeRoorkeeIndia

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