, Volume 33, Issue 3, pp 297–303 | Cite as

Il trattamento delle condropatie degenerative con tessuto adiposo autologo microframmentato

  • Arcangelo RussoEmail author
  • Francesca De Caro
  • Vincenzo Condello
  • Marco Collarile
  • Vincenzo Madonna

Treatment of degenerative cartilage lesions with micro-fragmented autologous adipose tissue


Osteoarthritis is a widespread pathology, with a prevalence of over 50% of the population, which leads to pain and functional limitation. At the moment, no surgical technique has been shown to be capable of real regeneration of the chondral layer. The new regenerative frontier seems to be represented by the self-ability of the Stromal Vascular Fraction (SVF) to preserve the cellular network, which is essential for cell regeneration. Several micro-fragmented adipose tissue extraction and processing systems have been refined in the past years and recent literature data show the biological effectiveness of this tissue, which plays a key role in restoring joint homeostasis, through the modulation of inflammation and pain. It will be necessary and important to understand whether this injective method can really be considered a “regenerative” option.


Conflitto di interesse

Gli autori Arcangelo Russo, Francesca De Caro, Vincenzo Condello, Marco Collarile e Vincenzo Madonna dichiarano di non avere alcun conflitto di interesse.

Consenso informato e conformità agli standard etici

Tutte le procedure descritte nello studio e che hanno coinvolto esseri umani sono state attuate in conformità alle norme etiche stabilite dalla dichiarazione di Helsinki del 1975 e successive modifiche. Il consenso informato è stato ottenuto da tutti i pazienti inclusi nello studio.

Human and Animal Rights

L’articolo non contiene alcuno studio eseguito su esseri umani e su animali da parte degli autori.


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Copyright information

© Società Italiana Ortopedici Traumatologi Ospedalieri d’Italia 2019

Authors and Affiliations

  • Arcangelo Russo
    • 1
    Email author
  • Francesca De Caro
    • 1
  • Vincenzo Condello
    • 1
  • Marco Collarile
    • 1
  • Vincenzo Madonna
    • 1
  1. 1.Dipartimento di Ortopedia, Chirurgia Articolare artroscopica e protesica e Traumatologia dello SportHumanitas-CastelliBergamoItalia

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