MRI-detected breast lesions: clinical implications and evaluation based on MRI/ultrasonography fusion technology

  • Kazuaki NakashimaEmail author
  • Takayoshi Uematsu
  • Taiyo L. Harada
  • Kaoru Takahashi
  • Seiichirou Nishimura
  • Yukiko Tadokoro
  • Tomomi Hayashi
  • Junichiro Watanabe
  • Takashi Sugino
Invited Review


Magnetic resonance imaging (MRI) is a highly sensitive imaging modality that frequently reveals additional breast lesions that are occult on mammography and ultrasonography (US) and are thus difficult to diagnose. It is important to investigate these MRI-detected suspicious lesions, which are associated with a fairly high rate of malignancy. In this review, we have discussed MRI/US fusion technology, a magnetic position tracking system that synchronizes real-time US and MRI to improve lesion detection and enables comparisons of MRI and US findings of the detected lesions. This combination increases the precision of second-look US. We hope that our review underscores the importance of understanding the US findings and histopathology of MRI-detected breast lesions, as this will enable radiologists to perform appropriate assessments.


Breast cancer MRI-detected lesion Second-look ultrasonography Fusion Real-time virtual sonography 



This paper was presented at the 104th annual meeting of the Radiological Society of North America in Chicago, 2018, where it received a Cum Laude award as an education exhibit. We thank Enago ( for the English language review.

Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflict of interest.


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Copyright information

© Japan Radiological Society 2019

Authors and Affiliations

  • Kazuaki Nakashima
    • 1
    Email author
  • Takayoshi Uematsu
    • 1
  • Taiyo L. Harada
    • 1
  • Kaoru Takahashi
    • 2
  • Seiichirou Nishimura
    • 2
  • Yukiko Tadokoro
    • 2
  • Tomomi Hayashi
    • 2
  • Junichiro Watanabe
    • 3
  • Takashi Sugino
    • 4
  1. 1.Department of Breast Imaging and Breast Interventional RadiologyShizuoka Cancer Center HospitalShizuokaJapan
  2. 2.Department of Breast SurgeryShizuoka Cancer Center HospitalShizuokaJapan
  3. 3.Department of Breast OncologyShizuoka Cancer Center HospitalShizuokaJapan
  4. 4.Department of PathologyShizuoka Cancer Center HospitalShizuokaJapan

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