Evaluation of coronary artery variations using dual-source coronary computed tomography angiography in neonates with transposition of the great arteries

  • Yuko OdawaraEmail author
  • Nobuko Kawamura
  • Yuzo Yamasaki
  • Joji Hashimoto
  • Shiro Ishikawa
  • Hiroshi Honda
Original Article



The purpose of this study was to investigate whether the origins and courses of the coronary arteries could be better assessed using ECG-gated dual-source computed tomography (CT) than with echocardiography in neonates with transposition of the great arteries (TGA).


A total of 17 neonates within 14 days old who underwent both echocardiography and retrospective ECG-gated coronary CT angiography were retrospectively reviewed. The patients were sedated and intubated during CT examinations, and CT images were obtained with a breath-hold. CT images were reconstructed by multiple cardiac phases, and the coronary artery assessment was performed in the most static phase. Coronary anomalies were classified by Shaher’s classification and validated by surgical findings.


CT correctly classified 16 of 17 cases (Shaher type 1: 7, type 2: 4, type 9: 3, type 3: 1, type 4: 2), whereas echocardiography classified only 8 of 17 cases correctly. Dual-source CT had a significantly higher diagnostic ability than echocardiography (p = 0.0078).


Dual-source coronary CT angiography has a higher diagnostic ability than echocardiography in the assessment of the origins and courses of the coronary arteries in neonates with TGA.


Transposition of the great arteries Coronary anomalies Cardiac CT Neonate 





Transposition of the great arteries


Congenital heart disease


Arterial switch operation


Multi-detector row computed tomography


Volume rendering


Multiplanar reformation


Volume CT dose index


Dose-length product


Standard deviation


Transthoracic echocardiography


Left circumflex artery


Right coronary artery


Left anterior descending artery



This work was supported by the Japan Society for the Promotion of Science (JSPS) KAKENHI (17K16452).

Compliance with ethical standards

Conflict of interest

Yamasaki Y: Bayer Healthcare Japan, Modest, Research Grant; Philips Electronics Japan, Modest, Research Grant. Other authors declare that they have no conflict of interest.

Ethical approval

Institutional Review Board approval at Fukuoka Children’s Hospital was obtained.

Informed consent

Written informed consent was waived due to the retrospective nature of the research.


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Copyright information

© Japan Radiological Society 2019

Authors and Affiliations

  • Yuko Odawara
    • 1
    • 2
    Email author
  • Nobuko Kawamura
    • 1
  • Yuzo Yamasaki
    • 3
  • Joji Hashimoto
    • 1
  • Shiro Ishikawa
    • 4
  • Hiroshi Honda
    • 5
  1. 1.Department of RadiologyFukuoka Children’s HospitalFukuokaJapan
  2. 2.Department of RadiologyHara Sanshin HospitalFukuokaJapan
  3. 3.Department of Molecular Imaging and Diagnosis, Graduate School of Medical SciencesKyushu UniversityFukuokaJapan
  4. 4.Department of CardiologyFukuoka Children’s HospitalFukuokaJapan
  5. 5.Department of Clinical Radiology, Graduate School of Medical SciencesKyushu UniversityFukuokaJapan

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