SPR Label-Free Biosensor with Oxide-Metal-Oxide-Coated D-Typed Optical Fiber: a Theoretical Study
- 194 Downloads
In this article, a surface plasmon resonance (SPR) biosensor based on D-typed optical fiber coated by Al2O3/Ag/Al2O3 film is investigated numerically. Resonance in near infrared with an optimized architecture is achieved. Refractive index sensitivity of 6558 nm/RIU (refractive index unit) and detection limit of 1.5 × 10−6 RIU, corresponding to 0.4357 nm/μM and detection limit of 23 nM in BSA (bovine serum albumin) concentration sensing, are obtained. The analysis of the performance of the sensor in gaseous sensing indicates that this proposed SPR sensor is much suitable for label-free biosensing in aqueous media.
KeywordsD-typed optical fiber Surface plasmon resonance Biological sensors Multilayer film
This work is supported by the Innovation Foundation for Doctor Dissertation of Northwestern Polytechnical University (Grant No.CX201818).
- 1.Schasfoort RB (2017) Handbook of surface plasmon resonance. Royal Society of ChemistryGoogle Scholar
- 18.Ghatak A, Thyagarajan K (1998) An introduction to fiber optics. Cambridge university pressGoogle Scholar
- 19.Barth J, Johnson R, Cardona M et al (1991) Handbook of optical constants of solids II. Academic Press, New YorkGoogle Scholar
- 26.An G, Li S, Cheng T et al. (2018) Ultra-stable D-shaped Optical Fiber Refractive Index Sensor with Graphene-Gold Deposited Platform. Plasmonics:1–9Google Scholar
- 27.Cennamo N, Zuppella P, Bacco D et al. (2016) SPR sensor platform based on a novel metal bilayer applied on D–shaped plastic optical fibers for refractive index measurements in the range 1.38–1.42. IEEE Sens. J 16:4822–4827Google Scholar