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Profile of Dr. Xiao-Fan Wang

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    References

    1. Alexander, P.B., Yuan, L., Yang, P., Sun, T., Chen, R., Xiang, H., Chen, J., Wu, H., Radiloff, D.R., and Wang, X.F. (2015). EGF promotes mammalian cell growth by suppressing cellular senescence. Cell Res 25, 135–138.

    2. Ali, A., Zhang, J., Bao, S., Liu, I., Otterness, D., Dean, N.M., Abraham, R. T., and Wang, X.F. (2004). Requirement of protein phosphatase 5 in DNA-damage-induced ATM activation. Genes Dev 18, 249–254.

    3. Bao, S., Ouyang, G., Bai, X., Huang, Z., Ma, C., Liu, M., Shao, R., Anderson, R.M., Rich, J.N., and Wang, X.F. (2004). Periostin potently promotes metastatic growth of colon cancer by augmenting cell survival via the Akt/PKB pathway. Cancer Cell 5, 329–339.

    4. Bao, S., Tibbetts, R.S., Brumbaugh, K.M., Fang, Y., Richardson, D.A., Ali, A., Chen, S.M., Abraham, R.T., and Wang, X.F. (2001). ATR/ATM-mediated phosphorylation of human Rad17 is required for genotoxic stress responses. Nature 411, 969–974.

    5. Bassing, C.H., Yingling, J.M., Howe, D.J., Wang, T., He, W.W., Gustafson, M.L., Shah, P., Donahoe, P.K., and Wang, X.F. (1994). A transforming growth factor beta type I receptor that signals to activate gene expression. Science 263, 87–89.

    6. Datto, M.B., Li, Y., Panus, J.F., Howe, D.J., Xiong, Y., and Wang, X.F. (1995). Transforming growth factor beta induces the cyclin-dependent kinase inhibitor p21 through a p53-independent mechanism. Proc Natl Acad Sci USA 92, 5545–5549.

    7. Guo, X., Ramirez, A., Waddell, D.S., Li, Z., Liu, X., and Wang, X.F. (2008). Axin and GSK3-ß control Smad3 protein stability and modulate TGF-ß signaling. Genes Dev 22, 106–120.

    8. Hu, J., Sun, T., Wang, H., Chen, Z., Wang, S., Yuan, L., Liu, T., Li, H.R., Wang, P., Feng, Y., et al. (2016). miR-215 is induced posttranscriptionally via HIF-Drosha complex and mediates gliomainitiating cell adaptation to hypoxia by targeting KDM1B. Cancer Cell 29, 49–60.

    9. Jian, H., Shen, X., Liu, I., Semenov, M., He, X., and Wang, X.F. (2006). Smad3-dependent nuclear translocation of beta-catenin is required for TGF-beta1-induced proliferation of bone marrow-derived adult human mesenchymal stem cells. Genes Dev 20, 666–674.

    10. Lin, H.Y., Wang, X.F., Ng- Eaton, E., Weinberg, R.A., and Lodish, H.F. (1992). Expression cloning of the TGF-ß type II receptor, a functional transmembrane serine/threonine kinase. Cell 68, 775–785.

    11. Ma, C., Rong, Y., Radiloff, D.R., Datto, M.B., Centeno, B., Bao, S., Cheng, A.W.M., Lin, F., Jiang, S., Yeatman, T.J., et al. (2008). Extracellular matrix protein beta ig-h3/TGFBI promotes metastasis of colon cancer by enhancing cell extravasation. Genes Dev 22, 308–321.

    12. Radiloff, D.R., Wakeman, T.P., Feng, J., Schilling, S., Seto, E., and Wang, X.F. (2011). Trefoil factor 1 acts to suppress senescence induced by oncogene activation during the cellular transformation process. Proc Natl Acad Sci USA 108, 6591–6596.

    13. Wang, H., Sun, T., Hu, J., Zhang, R., Rao, Y., Wang, S., Chen, R., McLendon, R.E., Friedman, A.H., Keir, S.T., et al. (2014). miR-33a promotes glioma-initiating cell self-renewal via PKA and NOTCH pathways. J Clin Invest 124, 4489–4502.

    14. Wang, X.F., Lin, H.Y., Ng- Eaton, E., Downward, J., Lodish, H.F., and Weinberg, R.A. (1991). Expression cloning and characterization of the TGF-ß type III receptor. Cell 67, 797–805.

    15. Yang, P., Li, Q.J., Feng, Y., Zhang, Y., Markowitz, G.J., Ning, S., Deng, Y., Zhao, J., Jiang, S., Yuan, Y., et al. (2012). TGF-ß-miR-34a-CCL22 signaling-induced Treg cell recruitment promotes venous metastases of HBV-positive hepatocellular carcinoma. Cancer Cell 22, 291–303.

    16. Yuan, L., Zhai, L., Qian, L., Huang, D., Ding, Y., Xiang, H., Liu, X., Thompson, J.W., Liu, J., He, Y.H., et al. (2018). Switching off IMMP2L signaling drives senescence via simultaneous metabolic alteration and blockage of cell death. Cell Res 28, 625–643.

    17. Zhang, Y., Yang, P., Sun, T., Li, D., Xu, X., Rui, Y., Li, C., Chong, M., Ibrahim, T., Mercatali, L., et al. (2013). miR-126 and miR-126* repress recruitment of mesenchymal stem cells and inflammatory monocytes to inhibit breast cancer metastasis. Nat Cell Biol 15, 284–294.

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    Profile of Dr. Xiao-Fan Wang. Sci. China Life Sci. (2020). https://doi.org/10.1007/s11427-020-1636-9

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