Advertisement

Extended synaptotagmins, peroxisome-endoplasmic reticulum contact and cholesterol transport

  • Hongyuan YangEmail author
Insight
  • 6 Downloads

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Antonny, B., Bigay, J., and Mesmin, B. (2018). The oxysterol-binding protein cycle: Burning off PI(4)P to transport cholesterol. Annu Rev Biochem 87, 809–837.CrossRefGoogle Scholar
  2. Chang, T.Y., Chang, C.C.Y., Ohgami, N., and Yamauchi, Y. (2006). Cholesterol sensing, trafficking, and esterification. Annu Rev Cell Dev Biol 22, 129–157.CrossRefGoogle Scholar
  3. Chu, B.B., Liao, Y.C., Qi, W., Xie, C., Du, X., Wang, J., Yang, H., Miao, H. H., Li, B.L., and Song, B.L. (2015). Cholesterol transport through lysosome-peroxisome membrane contacts. Cell 161, 291–306.CrossRefGoogle Scholar
  4. Das, A., Brown, M.S., Anderson, D.D., Goldstein, J.L., and Radhakrishnan, A. (2014). Three pools of plasma membrane cholesterol and their relation to cholesterol homeostasis. eLife 3, e02882.CrossRefGoogle Scholar
  5. Dong, J., Du, X., Wang, H., Wang, J., Lu, C., Chen, X., Zhu, Z., Luo, Z., Yu, L., Brown, A.J., et al. (2019). Allosteric enhancement of ORP1-mediated cholesterol transport by PI(4,5)P2/PI(3,4)P2. Nat Commun 10, 829.CrossRefGoogle Scholar
  6. Du, X., Brown, A.J., and Yang, H. (2015). Novel mechanisms of intracellular cholesterol transport: oxysterol-binding proteins and membrane contact sites. Curr Opin Cell Biol 35, 37–42.CrossRefGoogle Scholar
  7. Goldstein, J.L., DeBose-Boyd, R.A., and Brown, M.S. (2006). Protein sensors for membrane sterols. Cell 124, 35–46.CrossRefGoogle Scholar
  8. Hu, A., Zhao, X.T., Tu, H., Xiao, T., Fu, T., Wang, Y., Liu, Y., Shi, X.J., Luo, J., and Song, B.L. (2018). PIP4K2A regulates intracellular cholesterol transport through modulating PI(4,5)P2 homeostasis. J Lipid Res 59, 507–514.CrossRefGoogle Scholar
  9. Infante, R.E., and Radhakrishnan, A. (2017). Continuous transport of a small fraction of plasma membrane cholesterol to endoplasmic reticulum regulates total cellular cholesterol. eLife 6, e25466.CrossRefGoogle Scholar
  10. Koponen, A., Arora, A., Takahashi, K., Kentala, H., Kivelä, A.M., Jääskeläinen, E., Peränen, J., Somerharju, P., Ikonen, E., Viitala, T., et al. (2019). ORP2 interacts with phosphoinositides and controls the subcellular distribution of cholesterol. Biochimie 158, 90–101.CrossRefGoogle Scholar
  11. Liu, R., Zou, Y., Hong, J., Cao, M., Cui, B., Zhang, H., Chen, M., Shi, J., Ning, T., Zhao, S., et al. (2017). Rare Loss-of-Function Variants in NPC1 Predispose to Human Obesity. Diabetes 66, 935–947.CrossRefGoogle Scholar
  12. Luo, J., Jiang, L.Y., Yang, H., and Song, B.L. (2019). Intracellular cholesterol transport by sterol transfer proteins at membrane contact sites. Trends Biochem Sci 44, 273–292.CrossRefGoogle Scholar
  13. Marí, M., Caballero, F., Colell, A., Morales, A., Caballeria, J., Fernandez, A., Enrich, C., Fernandez-Checa, J.C., and García-Ruiz, C. (2006). Mitochondrial free cholesterol loading sensitizes to TNF- and Fas-mediated steatohepatitis. Cell Metab 4, 185–198.CrossRefGoogle Scholar
  14. Prinz, W.A. (2014). Bridging the gap: membrane contact sites in signaling, metabolism, and organelle dynamics. J Cell Biol 205, 759–769.CrossRefGoogle Scholar
  15. Vance, J.E., Hayashi, H., and Karten, B. (2005). Cholesterol homeostasis in neurons and glial cells. Seminars Cell Dev Biol 16, 193–212.CrossRefGoogle Scholar
  16. Wang, H., Ma, Q., Qi, Y., Dong, J., Du, X., Rae, J., Wang, J., Wu, W.F., Brown, A.J., Parton, R.G., et al. (2019). ORP2 Delivers Cholesterol to the Plasma Membrane in Exchange for Phosphatidylinositol 4, 5-Bisphosphate (PI(4,5)P2). Mol Cell 73, 458–473.e7.CrossRefGoogle Scholar
  17. Wilhelm, L.P., Wendling, C., Védie, B., Kobayashi, T., Chenard, M.P., Tomasetto, C., Drin, G., and Alpy, F. (2017). STARD3 mediates endoplasmic reticulum-to-endosome cholesterol transport at membrane contact sites. EMBO J 36, 1412–1433.CrossRefGoogle Scholar
  18. Wong, L.H., Gatta, A.T., and Levine, T.P. (2019). Lipid transfer proteins: the lipid commute via shuttles, bridges and tubes. Nat Rev Mol Cell Biol 20, 85–101.CrossRefGoogle Scholar
  19. Zhang, J.R., Coleman, T., Langmade, S.J., Scherrer, D.E., Lane, L., Lanier, M.H., Feng, C., Sands, M.S., Schaffer, J.E., Semenkovich, C.F., et al. (2008). Niemann-Pick C1 protects against atherosclerosis in mice via regulation of macrophage intracellular cholesterol trafficking. J Clin Invest 58.Google Scholar
  20. Zhao, K., and Ridgway, N.D. (2017). Oxysterol-binding protein-related protein 1L regulates cholesterol egress from the endo-lysosomal system. Cell Rep 19, 1807–1818.CrossRefGoogle Scholar
  21. Zhuang, L., Kim, J., Adam, R.M., Solomon, K.R., and Freeman, M.R. (2005). Cholesterol targeting alters lipid raft composition and cell survival in prostate cancer cells and xenografts. J Clin Invest 115, 959–968.CrossRefGoogle Scholar

Copyright information

© Science China Press and Springer-Verlag GmbH Germany, part of Springer Nature 2019

Authors and Affiliations

  1. 1.School of Biotechnology and Biomolecular Sciencesthe University of New South WalesSydneyAustralia

Personalised recommendations