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Risks of maternal prepregnancy overweight/obesity, excessive gestational weight gain, and bottle-feeding in infancy rapid weight gain: evidence from a cohort study in China

  • Shaoping Yang
  • Hong Mei
  • Hui Mei
  • Yan Yang
  • Na Li
  • Yafei Tan
  • Yiming Zhang
  • Dan Zhang
  • Yan Zhang
  • An’na Peng
  • Bin ZhangEmail author
Research Paper Special Topic: Futang pediatrics
  • 16 Downloads

Abstract

Rapid weight gain (RWG) in infants is associated with numerous health problems, and its risk factors are still unclear. We assessed 98,097 maternal-infant pairs from a population-based cohort study and followed up with them until the infants were 6 months old. We assessed the associations between maternal prepregnancy weight status; gestational weight gain; feeding pattern; and infants’ RWG at 0–1, 0–3, 1–3, and 3–6 months using multivariate unconditional logistic regression models, with controlled confounders. We found that maternal prepregnancy weight status, gestational weight gain, and feeding pattern at the 1st, 3rd, and 6th months had significant impacts on the infants’ RWG at each time period (P<0.05). Infants with overweight/obese mothers had a higher risk of RWG after birth, whereas those of mothers who experienced excessive gestational weight gain had higher risks of RWG from birth than the other groups (P<0.01). Infants who were formula-fed had a higher risk of RWG than breastfed infants at the same time point (P<0.01). In conclusion, maternal prepregnancy obesity, excessive gestational weight gain, and formula-feeding were risk factors for infants’ RWG during the first 6 months of life.

Keywords

rapid weight gain body mass index gestational weight gain breastfeeding influencing factor 

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Notes

Acknowledgements

We thank the participants for their cooperation. Thanks also go to colleagues who helped with anthropometric measurements and data management.

Compliance and ethics The author(s) declare that they have no conflict of interest. This study was approved by the Ethics Committee of Wuhan Children’s Hospital (Wuhan Maternal and Child Healthcare Hospital), Tongji Medical College, and Huazhong University of Science & Technology. Informed consent was obtained from all participants.

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Copyright information

© Science China Press and Springer-Verlag GmbH Germany, part of Springer Nature 2019

Authors and Affiliations

  • Shaoping Yang
    • 1
  • Hong Mei
    • 1
  • Hui Mei
    • 1
  • Yan Yang
    • 1
  • Na Li
    • 1
  • Yafei Tan
    • 1
  • Yiming Zhang
    • 1
  • Dan Zhang
    • 1
  • Yan Zhang
    • 1
  • An’na Peng
    • 1
  • Bin Zhang
    • 1
    Email author
  1. 1.Wuhan Children’s Hospital (Wuhan Maternal and Child Healthcare Hospital), Tongji Medical CollegeHuazhong University of Science & TechnologyWuhanChina

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