From golden rice to aSTARice, more than just two steps forward in a pathway

  • Wei-Cai Chen
  • Shan Lu
Research Highlight


  1. Al-Babili, S., and Beyer, P. (2005). Golden rice–five years on the road–five years to go? Trends Plant Sci 10, 565–573.CrossRefPubMedGoogle Scholar
  2. Cunningham, F.X. Jr., and Gantt, E. (1998). Genes and enzymes of carotenoid biosynthesis in plants. Annu Rev Plant Physiol Plant Mol Biol 49, 557–583.CrossRefPubMedGoogle Scholar
  3. Cunningham, F.X. Jr, and Gantt, E. (2011). Elucidation of the pathway to astaxanthin in the flowers ofAdonis aestivalis. Plant Cell 23, 3055–3069.CrossRefPubMedPubMedCentralGoogle Scholar
  4. Paine, J.A., Shipton, C.A., Chaggar, S., Howells, R.M., Kennedy, M.J., Vernon, G., Wright, S.Y., Hinchliffe, E., Adams, J.L., Silverstone, A.L., et al. (2005). Improving the nutritional value of golden rice through increased pro-vitamin a content. Nat Biotechnol 23, 482–487.CrossRefPubMedGoogle Scholar
  5. Sun, T., Yuan, H., Cao, H., Yazdani, M., Tadmor, Y., and Li, L. (2018). Carotenoid metabolism in plants: the role of plastids. Mol Plant 11, 58–74.CrossRefPubMedGoogle Scholar
  6. Ye, X. (2000). Engineering the provitamin A (β-carotene) biosynthetic pathway into (carotenoid-free) rice endosperm. Science 287, 303–305.CrossRefPubMedGoogle Scholar
  7. Zhou, F., Wang, C.Y., Gutensohn, M., Jiang, L., Zhang, P., Zhang, D., Dudareva, N., and Lu, S. (2017). A recruiting protein of geranylgeranyl diphosphate synthase controls metabolic flux toward chlorophyll biosynthesis in rice. Proc Natl Acad Sci USA 148, 201705689.CrossRefGoogle Scholar
  8. Zhu, Q., Yu, S., Zeng, D., Liu, H., Wang, H., Yang, Z., Xie, X., Shen, R., Tan, J., Li, H., et al. (2017). Development of “Purple Endosperm Rice” by engineering anthocyanin biosynthesis in the endosperm with a highefficiency transgene stacking system. Mol Plant 10, 918–929.CrossRefPubMedGoogle Scholar
  9. Zhu, Q., Zeng, D., Yu, S., Cui, C., Li, J., Li, H., Chen, J., Zhang, R., Zhao, X., Chen, L., et al. (2018). From golden rice to aSTARice: bioengineering astaxanthin biosynthesis in rice endosperm. Mol Plant Scholar

Copyright information

© Science in China Press and Springer-Verlag GmbH Germany, part of Springer Nature 2018

Authors and Affiliations

  1. 1.State Key Laboratory of Pharmaceutical Biotechnology, School of Life SciencesNanjing UniversityNanjingChina

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