HSS Journal ®

, Volume 15, Issue 3, pp 261–268 | Cite as

Validation of Physical Performance Tests in Individuals with Advanced Knee Osteoarthritis

  • Saurabh P. MehtaEmail author
  • Nathan Morelli
  • Caleb Prevatte
  • Derrick White
  • Ali Oliashirazi
Rehabilitation And Musculoskeletal Health / Original Article



Individuals with advanced osteoarthritis (OA) of the knee experience significant impairments in balance and in essential physical functions such as walking and rising from a chair. There is limited evidence on valid outcome measures to capture these impairments.


We sought to examine the construct validity of three physical performance measures in patients with advanced knee OA: a gait speed (GS) test, the Short Physical Performance Battery (SPPB), and the Timed Up and Go (TUG) test.


We designed a cross-sectional clinical measurement study in which patients with advanced knee OA completed two self-reported measures: the Knee Injury and Osteoarthritis Outcome Score—Physical Function Shortform (KOOS-PS) and a four-part numeric pain rating scale (Q-NPRS). They were also administered the GS test, TUG test, and SPPB. Convergent and divergent construct validity were assessed by examining relationships between the GS test, the SPPB, the TUG test, the KOOS-PS, and the Q-NPRS and calculating Pearson correlation coefficients (r). The scores for the GS, TUG test, and SPPB were compared with established normative values for age-matched healthy controls.


Forty-four subjects (mean age, 66.9 ± 8.1 years) participated in the study. The GS test showed low concordance with the SPPB component tests and the TUG test. The relationships between the physical performance measures and the self-reported measures were low. The scores for the GS test, TUG test, and SPPB in our sample were significantly worse when compared with age-matched normative values, indicating impairments in physical performance.


These results advance the understanding of the validity of the GS test, TUG test, and SPPB in demonstrating the impairments in physical performance that patients with advanced knee OA experience in walking, balancing, and rising from a chair. Future research should examine the reproducibility and responsiveness of the GS test, TUG test, and SPPB in patients with advanced knee OA, in order to facilitate the integration of these measures into clinical practice.


knee osteoarthritis gait speed physical functioning balance clinical measurement study 


Compliance with Ethical Standards

Conflict of Interest

Saurabh P. Mehta, PT, PhD, Nathan Morelli, PT, DPT, Caleb Prevatte, PT, DPT, and Derrick White, PT, DPT, declare that they have no conflicts of interest. Ali Oliashirazi, MD, reports grants and personal fees from DePuy Synthes and personal fees from Medtronic and from Zimmer Biomet, outside the submitted work.

Human/Animal Rights

All procedures followed were in accordance with the ethical standards of the responsible committee on human experimentation (institutional and national) and with the Helsinki Declaration of 1975, as revised in 2013.

Informed Consent

Informed consent was obtained from all patients for being included in this study.

Required Author Forms

Disclosure forms provided by the authors are available with the online version of this article.


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Copyright information

© Hospital for Special Surgery 2019

Authors and Affiliations

  1. 1.School of Physical TherapyMarshall UniversityHuntingtonUSA
  2. 2.Deptartment of Orthopedic Surgery, Joan C. Edwards School of MedicineMarshall UniversityHuntingtonUSA
  3. 3.Department of Rehabilitation Sciences, College of Health SciencesUniversity of KentuckyLexingtonUSA
  4. 4.Department of Physical TherapyRoper St. Francis Mount Pleasant HospitalMount PleasantUSA
  5. 5.Huntington Physical TherapyHuntingtonUSA

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