The influence of selected pharmaceuticals on biogas production from laboratory and real anaerobic sludge
- 28 Downloads
The presented study summarizes laboratory tests results to define the inhibition effect of selected pharmaceuticals on biogas production under anaerobic digestion conditions. Two sets of inhibition tests were realized: (i) with real anaerobic sludge (from municipal wastewater treatment plant (WWTP) where sludge is present and includes a wide spectrum of pharmaceuticals over a long period) and (ii) with laboratory sludge (sludge without pharmaceuticals). Methanogenic tests lasting 20 days were performed with three analgesics (diclofenac, ibuprofen, and tramadol), two antibiotics (amoxicillin and ciprofloxacin), β-blocker (atenolol), three psychoactive compounds (carbamazepine, caffeine, and cotinine), and a mixture of these compounds. All tests were performed with two concentrations of pharmaceuticals (10 μg/L and 500 μg/L). Results of the methanogenic tests showed the different behaviors of the investigated sludges in the presence of individual pharmaceuticals. Stimulation of anaerobic digestion was mostly detected for laboratory (unadapted) sludge (e.g., the addition of ibuprofen at a concentration of 500 μg/L increased biogas production by 61%). On the other hand, pharmaceuticals inhibited biogas production for real sludge (e.g., the addition of ciprofloxacin 500 μg/L decreased biogas production by 52%).
KeywordsSewage sludge Anaerobic fermentation Micropollutants Inhibition Stimulation Wastewater
This work was supported by the Slovak Research and Development Agency under the contract no. APVV 0122-12 and APVV 17-119.
- Fedorova G, Randak T, Lindberg RH, Grabic R (2013) Comparison of the quantitative performance of a Q-Exactive high-resolution mass spectrometer with that of a triple quadrupole tandem mass spectrometer for the analysis of illicit drugs in wastewater. Rapid Commun Mass Spectrom 27:1751–1762. https://doi.org/10.1002/rcm.6628 CrossRefGoogle Scholar
- ISO 13641-1 (2003) Water quality – determination of inhibition of gas production of anaerobic bacteria – part 1Google Scholar
- Ivanová L, Mackuľak T, Grabic R, Golovko O, Koba O, Staňová AV, Szabová P, Grenčíková A, Bodík I (2018) Pharmaceuticals and illicit drugs – a new threat to the application of sewage sludge in agriculture. Sci Total Environ 634:606–615. https://doi.org/10.1016/j.scitotenv.2018.04.001 CrossRefGoogle Scholar
- Martín J, Santos JL, Aparicio I, Alonso E (2015) Pharmaceutically active compounds in sludge stabilization treatments: anaerobic and aerobic digestion, wastewater stabilization ponds and composting. Sci Total Environ 503–504:97–104. https://doi.org/10.1016/j.scitotenv.2014.05.089 CrossRefGoogle Scholar
- Paíga P, Correia M, Fernandes MJ, Silva A, Carvalho M, Vieira J, Jorge S, Silva JG, Freire C, Delerue-Matos C (2019) Assessment of 83 pharmaceuticals in WWTP influent and effluent samples by UHPLC-MS/MS: hourly variation. Sci Total Environ 648:582–600. https://doi.org/10.1016/j.scitotenv.2018.08.129 CrossRefGoogle Scholar
- Park J, Yamashita N, Park C, Shimono T, Takeuchi DM, Tanaka H (2017) Removal characteristics of pharmaceuticals and personal care products: comparison between membrane bioreactor and various biological treatment processes. Chemosphere 179:347–358. https://doi.org/10.1016/j.chemosphere.2017.03.135 CrossRefGoogle Scholar
- Stuckey DC, Owen WF, McCarty PL (1980) Anaerobic toxicity evaluation by batch and semi-continuous assays. J Water Pollut Control Fed 52:720–729Google Scholar
- Verlicchi P, Zambello E (2015) Pharmaceuticals and personal care products in untreated and treated sewage sludge: occurrence and environmental risk in the case of application on soil - a critical review. Sci Total Environ 538:750–767. https://doi.org/10.1016/j.scitotenv.2015.08.108 CrossRefGoogle Scholar