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Ambient air pollution and risk of type 2 diabetes in the Chinese

  • Hui Li
  • Donghui Duan
  • Jiaying Xu
  • Xiaoqi Feng
  • Thomas Astell-Burt
  • Tianfeng He
  • Guodong Xu
  • Jinshun Zhao
  • Lina Zhang
  • Dingyun YouEmail author
  • Liyuan Han
Research Article
  • 56 Downloads

Abstract

We performed a time series analysis to investigate the potential association between exposure to ambient air pollution and type 2 diabetes (T2D) incidence in the Chinese population. Monthly time series data between 2008 and 2015 on ambient air pollutants and incident T2D (N = 25,130) were obtained from the Environment Monitoring Center of Ningbo and the Chronic Disease Surveillance System of Ningbo. Relative risks (RRs) and 95% confidence intervals (95% CIs) of incident T2D per 10 μg/m3 increases in ambient air pollutants were estimated from Poisson generalized additive models. Exposure to particulate matter < 10 μm (PM10) and sulfur dioxide (SO2) was associated with increased T2D incidence. The relative risks (RRs) of each increment in 10 μg/m3 of PM10 and SO2 were 1.62 (95% CI, 1.16–2.28) and 1.63 (95% CI, 1.12–2.38) for overall participants, whereas for ozone (O3) exposure, the RRs were 0.78 (95% CI, 0.68–0.90) for overall participants, 0.78 (95% CI, 0.69–0.90) for males, and 0.78 (95% CI, 0.67–0.91) for females, respectively. Exposure to PM10 and SO2 is positively associated with T2D incidence, whereas O3 is negatively associated with T2D incidence.

Keywords

Ambient air pollutants Type 2 diabetes Incidence 

Notes

Funding information

The study is supported by grants from National Natural Science Foundation of China (81402745); Natural Science Foundation of Zhejiang Province (LY17H260002); K. C. Wong Magna Fund in Ningbo University; the Ministry of Education, Humanities, and Social Sciences project (14YJC630046); China Postdoctoral Science Foundation funded project (156458); Jiangsu Postdoctoral Science Foundation funded project (1601121B); Ningbo University Scientific Research Fund (XKL14D2098); National Natural Science Foundation of Ningbo (2017A610219); and Ningbo Scientific Innovation Team for Environmental Hazardous Factor Control and Prevention (2016C51001).

Compliance with ethical standards

The study was approved by the institutional review board of Ningbo Municipal Center for Disease Prevention and Control. All the participants provided written informed consent.

Competing interest

The authors declare that they have no competing interests.

Supplementary material

11356_2019_4971_MOESM1_ESM.docx (434 kb)
ESM 1 (DOCX 434 kb)

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Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2019

Authors and Affiliations

  1. 1.Ningbo Municipal Center for Disease Control and PreventionNingboChina
  2. 2.Department of Epidemiology, School of Public Health and Tropical MedicineTulane UniversityNew OrleansUSA
  3. 3.Population Wellbeing and Environment Research Lab (Power Lab), Faculty of Social SciencesUniversity of WollongongWollongongAustralia
  4. 4.Early Start, Faculty of Social SciencesUniversity of WollongongWollongongAustralia
  5. 5.Menzies Centre for Health PolicyUniversity of SydneySydneyAustralia
  6. 6.Department of Preventive MedicineMedical School of Ningbo UniversityNingboChina
  7. 7.School of Public HealthKunming Medical UniversityKunmingChina

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