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Residue behavior and risk assessment of cymoxanil in grape under field conditions and survey of market samples in Guangzhou

  • Jianxiang Huang
  • Qian Ye
  • Kai Wan
  • Fuhua Wang
Research Article

Abstract

A simple and fast method based on liquid chromatography-tandem mass spectrometry (LC-MS/MS) was developed for cymoxanil residue analysis in grape. Sample preparation based on solid-liquid extraction was optimized without using adsorbent for purification. Recoveries were 79.8–109.5% with relative standard deviations (RSDs) of 2.5–9.4% at fortified levels from 0.001 to 0.50 mg/kg. The limit of detection (LOD) was 0.3 μg/kg. Field trials were conducted to explore the dissipation and terminal residue behavior of cymoxanil in grape. Results showed that the half-lives of cymoxanil were from 0.5 to 0.7 days. Terminal residues were from below the limit of quantification (LOQ) to 0.363 mg/kg. Dietary exposure risk assessment revealed that the risk quotients (RQs) were much less than 1. It was concluded that cymoxanil in grape raised negligible concerns to human health under field conditions. Sixty grape samples from Guangzhou market were found to be free of cymoxanil. The proposed study would provide reference for appropriate use of cymoxanil in grape planting in China.

Keywords

Cymoxanil Grape Residue Risk assessment Survey Guangzhou 

Notes

Funding

This research was financially supported by the National Natural Science Foundation of China (no. 21305019) and National Program for Quality and Safety Risk Assessment of Agricultural Products of China (nos. GJFP2014001, GJFP2015001, and GJFP2016002).

Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflict of interest.

Supplementary material

11356_2018_3890_MOESM1_ESM.docx (16 kb)
ESM 1 (DOCX 15 kb)

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Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2018

Authors and Affiliations

  • Jianxiang Huang
    • 1
    • 2
    • 3
  • Qian Ye
    • 1
    • 2
    • 3
  • Kai Wan
    • 1
    • 2
    • 3
  • Fuhua Wang
    • 1
    • 2
    • 3
  1. 1.Public Monitoring Center for Agro-productGuangdong Academy of Agricultural SciencesGuangzhouChina
  2. 2.Key Laboratory of Testing and Evaluation for Agro-product Quality and SafetyMinistry of Agriculture and Rural Affairs, People’s Republic of ChinaGuangzhouChina
  3. 3.Laboratory of Quality and Safety Risk Assessment for Agro-product (Guangzhou)Ministry of Agriculture and Rural Affairs, People’s Republic of ChinaGuangzhouChina

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