Acute effects of air pollution on type II diabetes mellitus hospitalization in Shijiazhuang, China
Air pollution has been considered as an important contributor to diabetes development. However, the evidence is fewer in developing countries where air pollution concentrations were much higher. In this study, we conduct a time-series study to investigate the acute adverse effect of six air pollutants on type II diabetes mellitus (T2DM) hospitalization in Shijiazhuang, China. An over-dispersed passion generalized addictive model adjusted for weather conditions, day of the week, and long-term and seasonal trends was used. Finally, a 10-μg/m3 increase of fine particulate matter (PM2.5), inhalable particulate matter (PM10), sulfur dioxide (SO2), nitrogen dioxide (NO2), and carbon monoxide (CO) corresponded to 0.53% (95% confidence interval = 0.22–0.83), 0.32% (95% CI = 0.10–0.55), 0.55% (95% CI = 0.04–1.07), 1.27% (95% CI = 0.33–2.22), and 0.04% (95% CI = 0.02–0.06) increment of T2DM hospitalization, respectively. The effects of PM2.5, PM10, and CO were robust when adjusted for co-pollutants. The associations appeared to be a little stronger in the cool season than in the warm season. And stronger associations were found in male and elderly (≥ 65 years) than in female and younger people (35–65 years). Our results contribute to the limited data in the scientific literature on acute effects of air pollution on type II diabetes mellitus in developing countries. Main findings: This is the first adverse effect evidence of air pollution on T2DM in Shijiazhuang, a severely polluted city in China. Males were more vulnerable than females in severe pollution.
KeywordsAir pollution Type II diabetes mellitus Hospitalization Time-series study
The study was supported by the National Natural Science Foundation of China (21677136), the Ph.D. Research Project of Xinxiang Medical University (XYBSKYZZ201804), Key Scientific Research Projects in Universities of Henan Province (19B330004), and Peak Subject Project of Public Health in Xinxiang Medical University.
Compliance with Ethical Standards
Conflict of Interest
The authors declare they have no actual or potential competing financial interests.
This study does not involve experimental animals or individual information of human subjects.
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