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Veterinary Research Communications

, Volume 42, Issue 3, pp 209–217 | Cite as

The synergistic effect of organic acids, phytochemicals and a permeabilizing complex reduces Salmonella Typhimurium 1,4,[5],12:i-shedding in pigs

  • Jessica Ruggeri
  • Fabio Foresti
  • Roberta Pavesi
  • Alessia Terrini
  • Francesca Giudici
  • Diego Padoan
  • Attilio Corradi
  • Maria Cristina Ossiprandi
  • Paolo Pasquali
  • Giovanni Loris Alborali
Original Article
  • 149 Downloads

Abstract

Salmonella Typhimurium (including S.Typhimurium 1,4,[5],12:i-) and other enteric pathogens cause acute infection in pigs during the weaning stage, often evolving into chronic infections responsible for the introduction of zoonotic bacteria into the slaughterhouse and thus determining carcass contamination. In addition to being zoonotic hazards, these pathogens are responsible for economic losses in affected farms. Traditionally, antibiotic treatments have been largely administered in order to reduce the infection burden but it favored, as a direct consequence, an increase in the number of multi-drug resistance strains. In order to overcome antibiotic-resistance concerns, new alternative control strategies should be developed. In this context, a blend of organic acids, phytochemicals and a permeabilizing complex, administered in feed (Group A - 459 piglets) or water (Group B – 458 piglets), was tested in field conditions for its capability of reducing Salmonella-infection in weaned piglets of an endemic farm. Data recorded were compared to results of a control group (Group C - 456 piglets). Zootechnical parameters were recorded in all animals, while microbiological, serological and PCR analyses were conducted in 15 piglets for each group. Results demonstrated that additive administered in feed improved animal weight gain (better average daily gain [A.D.G.] and increment), and rapidly reduced Salmonella-shedding in feces. Administration of additive in feed gave better results than in water.

Keywords

Salmonella Typhimurium 1,4,[5],12:i- Organic acids Phytochemicals Swine 

Abbreviations

A.D.G.

average daily gain

AIAO

all in all out

BGA

brilliant green agar

Bp

base pair

BPW

buffered peptone water

FCR

feed conversion rate

MSRV

modified semisolid rappaport-vassiliadis

OD

optical density

PRRSV

porcine reproductive and respiratory virus

PCV-type2

porcine circovirus type 2

XLD

xylose-lysine-deoxycholate

ZnO

zinc oxide

Notes

Acknowledgements

Special thanks to Eurostreet società cooperativa for the English writing assistance.

Compliance with ethical standards

Conflicts of interest

The authors declare that they have no conflict of interest.

Human participants and/or animals

Animals were treated with products that are registered for administration in breeding animals and which the farmer had commonly used. Procedures involving animals were limited to blood and fecal sampling with a ten-day interval. In conclusion, all procedures performed in studies involving animals were in accordance with ethical standards of practice, particularly with those of the National Legislation of Animal Welfare.

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Copyright information

© Springer Science+Business Media B.V., part of Springer Nature 2018
corrected publication August/2018

Authors and Affiliations

  • Jessica Ruggeri
    • 1
  • Fabio Foresti
    • 2
  • Roberta Pavesi
    • 2
  • Alessia Terrini
    • 1
  • Francesca Giudici
    • 1
  • Diego Padoan
    • 3
  • Attilio Corradi
    • 4
  • Maria Cristina Ossiprandi
    • 4
  • Paolo Pasquali
    • 5
  • Giovanni Loris Alborali
    • 1
  1. 1.Istituto Zooprofilattico Sperimentale della Lombardia e dell’Emilia Romagna [Experimental Zooprophylactic Institute of Lombardy and Emilia Romagna]BresciaItaly
  2. 2.GKL S.a.s, Casalfiumanese (Bo)CasalfiumaneseItaly
  3. 3.Biomin GmbH GetzersdorfGetzersdorfAustria
  4. 4.Department of Veterinary SciencesUniversity of ParmaParmaItaly
  5. 5.Department of Veterinary Public Health and Food SafetyIstituto Superiore di SanitàRomeItaly

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