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Spontaneous renal hemorrhage: critical analysis of different lines of management in non-traumatic patients: a single tertiary center experience

  • M. A. ElbasetEmail author
  • Mohamad H. Zahran
  • Ramy EL-Baz
  • Mohamed Badawy
  • Yasser Osman
Urology - Original Paper
  • 19 Downloads

Abstract

Purpose

To assess clinical presentation and outcomes of different treatment strategies in cases of spontaneous renal hemorrhage (SRH).

Methods

A retrospective analysis of patients with SRH between 2000 and 2018 was performed. Patients’ demographics, clinical presentation, laboratory and radiological investigations, and different lines of treatment were retrieved. The primary outcome was to assess the predictors of the success of conservative treatment. The secondary outcome was to assess the long-term renal function outcome comparing serum creatinine, e GFF, and CT-assessed renal volume at last follow-up with baseline values.

Results

The study included 42 (23 males and 19 women) patients with mean ± SD age was 48.1 ± 17.8 years. Conservative management was successful in 19 (46%) patients. Trans-arterial embolization (TAE) was performed in 13 patients (30%) to control active bleeding. Ten patients (25%) required surgical exploration and nephrectomy. Lower serum creatinine (P = 0.003), higher prothrombin concentration (P = 0.04), lower hematoma size (P = 0.02), and non-AML lesions (P = 0.03) were independent predictors of conservative management success. Unlike the TAE-treated group, serum creatinine increased significantly (P = 0.04) with a significant decrease in e-GFR (P = 0.02) and renal volume (P < 0.001) of affected kidneys at last follow-up after conservative treatment.

Conclusion

Although SRH is a life-threatening condition, conservative treatment is successful in a certain subset of patients. However, it is associated with significant deterioration of the affected kidney function as well as renal volume.

Keywords

Spontaneous Renal Hemorrhage Trans-arterial embolization (TAE) Trauma Renal function 

Notes

Author contribution

Elbaset MA: patients’ follow-up and statistical analysis and manuscript writing; Mohamad H Zahran: manuscript editing; Ramy  EL-Baz: data collection; Mohamed Badawy: radiology data supervision; Yasser Osman: study supervision and manuscript revision.

Funding

Authors states that there was no funding received.

Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflict of interest.

Human and animal rights

All procedures in this study involving human participants were in accordance with the ethical standards of the institutional committee and with the 1964 Helsinki Declaration and its later amendments.

Informed consent

Informed consent was obtained from all individual participants included in the study.

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Copyright information

© Springer Nature B.V. 2019

Authors and Affiliations

  1. 1.Urology Department, Urology and Nephrology CenterMansoura UniversityMansouraEgypt
  2. 2.Radiology Department, Urology and Nephrology CenterMansoura UniversityMansouraEgypt

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