Florid mesothelial hyperplasia of the tunica vaginalis: report of two cases with immunohistochemical findings
Mirroring reactive lesions in other surface membranes, mesothelial hyperplasia of the tunica vaginalis may be so florid that it can mimic malignant mesothelioma or adenocarcinoma. In the largest series reported to date (n = 12), by Epstein et al. , 75% of all cases are associated with hydrocele and 1 case (8%) with hematocele. Before that series, mesothelial hyperplasia of tunica vaginalis was thought to be associated more commonly with hernial sacs, while malignant mesothelioma would be more associated with hydrocele sacs . Awareness of that florid reactive condition is important, since true malignant mesothelioma of tunica vaginalis is a rare tumor—0.3% to 5% of all malignant mesotheliomas, with about 100 cases reported so far .
KeywordsMesothelial hyperplasia Testis Tunica vaginalis
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The authors declare that they have no conflict of interest.
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