Hormonal stimulation of spermatogenesis: a new way to treat the infertile male with non-obstructive azoospermia?
We herein report a full-term delivery of a healthy child obtained with aid of intracytoplasmic sperm injection (ICSI) in an infertile couple with non-obstructive azoospermia (NOA) and severe endometriosis, following hormonal stimulation of spermatogenesis, cryopreservation of ejaculated spermatozoa using the cell sleeper method, and subsequently ICSI.
A 28-year-old male and his 32-year-old spouse were admitted to The Fertility Clinic Skive due to primary infertility. The couple had tried to conceive for 2 years. The medical history of the male revealed bilateral cryptorchidism and testicles which only fully descended to the scrotum at the age of 12. The reason why the condition was left untreated is unknown. No previous medical treatment or surgery was recorded. The clinical examination of the patient revealed a normal virilized male with both testicles in the scrotum, both having a volume of approximately 8 ml. We noted no abnormalities of the...
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Conflict of interest
- 3.Esteves SC (2015) Clinical management of infertile men with nonobstructive azoospermia. Asian J Androl 17(3):459–470Google Scholar