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Non-infectious causes that increase early and mid-to-late pregnancy loss rates in a crossbreed dairy herd

  • Fransergio Souza
  • Luisa Cunha Carneiro
  • João Cesar
  • Ricarda Maria dos Santos
Regular Articles

Abstract

High reproductive performance is an element factor for profitability in dairy herds; although, pregnancy loss of non-infectious nature during early and mid-to-late embryonic period is increasing in dairy cattle. Based on that, the present study aimed to determine the incidence of pregnancy loss before and after 60 days of insemination, and to identify some non-infectious causes that could enhance it. The herd was composed by 600 crossbred dairy cows and those with a corpus luteum (CL) were treated with prostaglandinF2α, then inseminated, on the other hand, those without a CL were submitted to a timed artificial insemination protocol (TAI). Pregnancy losses rates were analyzed by logistic regression by SAS, and differences were considered significant when P < 0.05. The overall pregnancy loss and mid-to-late pregnancy loss were not affected by animal category (P > 0.05); although, early pregnancy loss was higher in cows than in heifers (11.90 vs. 3.39%). The early pregnancy loss was higher in those cows that calved on spring/summer when compared to those calved on fall/winter (9.22% vs. 16.11%), moreover, those inseminated during spring/summer tended to have higher early pregnancy loss when compared to those inseminated on fall/winter (13.35% vs. 8.57%). In conclusion, when some of non-infectious causes were evaluated, it was observed that cows that calved on spring/summer had higher pregnancy loss. At this point, strategies should be developing to minimize pregnancy loss in dairy herds, as it could be considered an important reproductive problem.

Keywords

Dairy system Embryonic loss Fetal loss Reproduction efficiency 

Notes

Funding information

This study is financially supported by the Research Support Foundation of Minas Gerais state, Brazil, (FAPEMIG).

Compliance with ethical standards

Statement of animal right

In the conduct of this study, all rules, regulations and ethical considerations recommended by Brazil country and other reputable authorities have been carefully observed. The design of this study was approved by the committee of care and use of animals from Federal University of Uberlândia (CEUA/UFU/2002).

Conflict of interest

The authors declare that they have no conflict of interest.

References

  1. Bartolomé, J.A. Silvestre, F.T. Kamimura, S. Arteche, A.C.M. Melendez, P. Kelbert, D. McHale, J. Swift, K. Archbald, L.F. Thatcher, W.W. 2005. Resynchronization of ovulation and timed insemination in lactating dairy cows I: use of the Ovsynch and Heatsynch protocols after non-pregnancy diagnosis by ultrasonography. Theriogenology, 6, 1617–1627.CrossRefGoogle Scholar
  2. Carpenter, T.E. Chrièl, M. Andersen, M.M. Wulfson, L. Jensen, A.M. Houe, H. Greiner, M. 2006. An epidemiologic study of late-term abortions in dairy cattle in Denmark. Preventive Veterinary Medicine, 77,215–29.CrossRefGoogle Scholar
  3. Cartmill, J.A. El-Zarkouny, S.Z. Hensley, B.A, Lamb, G.C. Stevenson, J.S. 2001a. Stage of cycle, incidence and timing of ovulation, and pregnancy rates in dairy cattle after three timed breeding protocols. Journal of Dairy Science. 80, 3386–3398.Google Scholar
  4. Cartmill, J.A, El Zarkouny, S.Z. Hensley, B.A. Lamb, G.C. Stevenson, J.S. 2001b. Stage of cycle, incidence, and timing of ovulation, and pregnancy rates in dairy cattle after three timed breeding protocols. Journal of Dairy Science, 84:1051–1059.CrossRefGoogle Scholar
  5. Chebel, R.C. Santos, J.E.P. Cerri, R.L.A. Galvao, K.N. Juchem, S.O. Thatcher, WW. 2003. Effect of resynchronization with GnRH on day 21 after artificial insemination on pregnancy rate and pregnancy loss in lactating dairy cows. Theriogenology. 60,1389–99.CrossRefGoogle Scholar
  6. Chebel, R.C. Santos, J.E.P. Reynolds, J.P. Cerri, R.L.A. Juchem, S.O. Overton, M. 2004. Factors affecting conception rate after artificial insemination and pregnancy loss in lactating dairy cows. Animal of Reproduction Science, 84, 239–255.CrossRefGoogle Scholar
  7. De Vries, A. Economic value of pregnancy in dairy cattle. 2006. Journal of Dairy Science, 89, 3876–3885.CrossRefGoogle Scholar
  8. Ettema, J.F. and Santos, J.E.P. 2004. Impact of age at calving on lactation, reproduction, health, and income in first-parity Holstein on commercial farms. Journal of Dairy Science, 87, 2730–2742.CrossRefGoogle Scholar
  9. Ferguson, J.D. Galligan, D.T. Thomsen, N. 1994. Principal descriptors of body condition score in Holstein cows. Journal of Dairy Science, 77, 2695–2703.CrossRefGoogle Scholar
  10. García-Ispierto, I. López-Gatius, F. Santolaria, P. Yániz, J.L. Nogareda, C. López-Béjar, M. De Rensis, F. 2006. Relationship between heat stress during the peri-implantation period and early fetal loss in dairy cattle. Theriogenology. 65, 799–807.CrossRefGoogle Scholar
  11. Grimard, B. Freret, S. Chevallier, A. Pinto, A. Ponsar, C. Humblot, P. 2006) Genetic and environmental factors influencing first service conception rate and late embryonic /foetal mortality in low fertility dairy herds. Animal of Reproduction Science. 91,31–44.CrossRefGoogle Scholar
  12. Humblot, P. 2001. Use of pregnancy specific proteins and progesterone assays to monitor pregnancy and determine the timing, frequencies and sources of embryonic mortality in ruminants. Theriogenology. 56, 1417–1433.CrossRefGoogle Scholar
  13. Jousan, F D., Drost, M., Hansen, P.J. 2005. Factors associated with early and mid-to-late fetal loss in lactating and nonlactating Holstein cattle in a hot climate. Journal of Animal Science. 83, 1017–1022.CrossRefGoogle Scholar
  14. Labèrnia, J. López-Gatius, F. Santolaria, P. López-Béjar, M. Rutllant J. 1996. Influence of management factors on pregnancy attrition in dairy cattle. Theriogenology. 45, 1247–1253.CrossRefGoogle Scholar
  15. Lee, J.Y. and Kim, I.H. 2007. Advancing parity is associated with high milk production at the cost of body condition and increased periparturient disorders in dairy herds. Journal of Veterinarian Science, 7, 161–166.Google Scholar
  16. López-Gatius, F. Santolaria, P. Yaniz, J. Rutllant, J, López-Béjar, M. 2002. Factors affecting pregnancy loss from gestation day 38 to 90 in lactating dairy cows from a single herd. Theriogenology, 57, 1251–1261.CrossRefGoogle Scholar
  17. López-Gatius, F. Santolaria, P. Yániz, J.L. Garbayo, J.M.,Hunter, R.H.F. 2004. Timing of early foetal loss for single and twin pregnancies in dairy cattle. Reproduction in Domestic Animals, 39, 429–433.CrossRefGoogle Scholar
  18. Moontiel-Olguín, L.J. Estrada-Cortés, E. Espinosa-Martínez, M.A. Mellado, M. Hernandëz-Vélez, J.O. Martínez-Trejo, G. Ruíz-López, F.J. Vera-Avila, H.R. 2018. Risk factors associated with reproductive performance in small-scale dairy farms in Mexico. Tropical Animal Health and Production, available at  https://doi.org/10.1007/s11250-018-1681-9
  19. Moore, K. and Thatcher, W.W. 2006. Major advances associated with reproduction in dairy cattle. Journal of Dairy Science, 89, 1254–1266.CrossRefGoogle Scholar
  20. Moore, D.A. Overton, M.W. Chebel, R.C. Truscott, M.L, BonDurant, R.H.2005. Evaluation of factors that affect embryonic loss in dairy cattle. Journal of the American Veterinary Medical Association, 226, 1112–1118.CrossRefGoogle Scholar
  21. Moreira, F. Orlandi, C. Risco C.A. Mattos, R. Lopes, F. Thatcher, W.W. 2001. Effects of presynchronization and bovine somatotropin on pregnancy rates to a time artificial insemination protocol in lactating dairy cows. Journal of Dairy Science, 84, 1646–1659.CrossRefGoogle Scholar
  22. Naional Research Council (NRC). 2001. Nutrient requirements of dairy cattle. 7th ed. Washington: National Academy Press, 408 p.Google Scholar
  23. Radigonda, V.L., Pereira, G.R., da Cruz Favaro, P., Barca Júnior, F.A., Borges, M.H.F., Galdioli, V.H.G., Júnior, C.K. 2017. Infrared thermography relationship between the temperature of the vulvar skin, ovarian activity, and pregnancy rates in Braford cows. Tropical Animal Health and Production, v.49 (8), 1787–91.CrossRefGoogle Scholar
  24. Rutigliano, H.M., Lima, F.S., Cerri, L.A., Greco, L.F., Vilela, J.M., Magalhaes, V., Silvestre, F.T., Thatcher, W.W. Santos, J.E.P. 2008. Effects of method of presynchronization and source of selenium on uterine health and reproduction in dairy cows. Journal of Dairy Science, 91, 3323–36.CrossRefGoogle Scholar
  25. Santos, J.E.P. Thatcher, W.W. Chebel, R.C. Cerri, R.L.A Galvão, K.N. 2004a. The effect of embryonic death rates in cattle on the efficacy of estrous synchronization programs. Animal Reproduction Science, 82–83, 513–535.CrossRefGoogle Scholar
  26. Santos, J.E.P. Cerri, R.L.A. Ballou, M.A. Higginbotham, G.E. Kirk, J.H. 2004b. Effect of timing of first clinical mastitis occurrence on lactational and reproductive performance of Holstein dairy cows. Animal Reproduction Science, 80, 31–45.CrossRefGoogle Scholar
  27. Santos, J.E.P. Rutigliano, H.M. Sá, M.F. 2009. Risk factors for resumption of postpartum estrous cycles and embryonic survival in lactating dairy cows. Animal Reproduction Science, 110, 207–221.CrossRefGoogle Scholar
  28. Silke, V. Diskin, M.G. Kenny, D.A. Boland, M.P. Dillon, P. Mee, J.F. Sreenan, JM. 2002. Extent, pattern and factors associated with late embryonic loss in dairy cows. Animal Reproduction Science, 71, 1–12.CrossRefGoogle Scholar
  29. Silva-del-Río, N. Colloton, J.D. Fricke, P.M. 2009. Factors affecting pregnancy loss for single and twin pregnancies in a high-producing dairy herd. Theriogenology, 71,1462–1471.CrossRefGoogle Scholar
  30. Smith, M.W. Stevenson, J.S. 1995. Fate of the dominant follicle, embryonal survival and pregnancy rates in dairy cattle treated with prostaglandin F2a and progestins in the absence or presence of a functional corpus luteum. Animal Science, 73, 3743–3751.CrossRefGoogle Scholar
  31. Sreenan, J.M. Diskin, M.G., Moris, D.G. 2001. Embryo survival rate in cattle: a major limitation to the achievement of high fertility. Animal Science, 26, 93–104.Google Scholar
  32. Statistical Analyses System – SAS. User’s guide. Cary: 2000. CD-ROM.Google Scholar
  33. Thurmond, M.C. Picanso, J.P. Jameson, C.M. 1990. Considerations for use of descriptive epidemiology to investigate fetal loss in dairy cows. Journal of American Veterinary Medical Association, 197,1305–1312.Google Scholar
  34. Vanroose G., De Kruif, A., Van Soom, A. 2000. Embryonic mortality and embryo-pathogen interactions. Animal Reproduction Science, 60-61, 31–143.CrossRefGoogle Scholar
  35. Walsh, S.W. Williams, E.J. Evans, A.C.Q. 2011. A review of the causes of poor fertility in high milk producing dairy cows. Animal Reproduction Science, 123, 27–138.CrossRefGoogle Scholar
  36. Wiltbank, M.C. Baez, G.M. Garcia-Guerra, A. Toledo, M.Z. Monteiro, P.L.J. Melo, L.F. Ochoa, J.C. Santos, J.E.P. Sartori, R. 2016. Pivotal periods for pregnancy loss during the first trimester of gestation in lactating dairy cows. Theriogenology, 86, 239–253.CrossRefGoogle Scholar

Copyright information

© Springer Nature B.V. 2018

Authors and Affiliations

  1. 1.Faculty of Veterinary MedicineFederal University of UberlândiaUberlândiaBrazil
  2. 2.Laboratory of Teaching and Research in Pathology of Reproduction, Center of Biotechnology in Animal Reproduction, Department of Animal Reproduction, School of Veterinary Medicine and Animal ScienceUniversity of São Paulo (USP)PirassunungaBrazil

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