Journal of Thrombosis and Thrombolysis

, Volume 47, Issue 1, pp 134–139 | Cite as

Long-term follow-up of the stenting across the iliocaval confluence in patients with iliac venous lesions

  • Xicheng ZhangEmail author
  • Yuanhu Jing
  • Hongfei Sang
  • Zhaolei Chen
  • Yuan Sun
  • Xiaoqiang Li


Stent implantation is the common treatment method for iliac vein (IV) occlusion. IV stents usually enter into the inferior vena cava (IVC) to partially or completely cover the contralateral IV, but it is still uncertain whether this can increase the risk of thrombosis in the contralateral IV. The purpose of this study was to investigate the effect of the stent position on the bilateral IVs patency. A total of 261 patients with symptomatic IV lesions, including 177 patients with non-thrombotic iliac vein lesions (NIVLs) and 84 patients with thrombotic iliac vein lesions (TIVLs), were implanted with IV stents between July 2007 and June 2017. The data of these patients were retrospectively studied. The follow-up time was 6–114 months, and the median time was 62 months. A total of 183 cases had stenting into the IVC for more than 5 mm. The incidence of thrombosis in the contralateral IV was only 0.55% (1/183). A total of 17 short- and long-term cumulative cases had ipsilateral thrombosis on the stent side. There was no significant difference between the incidence of patients (8.79%, 7/78) with stenting into the IVC for less than 5 mm and those with more than 5 mm (5.46%, 10/183, P = 0.287). However, in the TIVLs group, the incidence of ipsilateral thrombosis between stenting positions less than 5 mm (29.6%, 8/27) and those more than 5 mm (8.77%, 5/57) was significantly different (P = 0.022). Stent implantation for NIVLs had an excellent long-term patency rate; the primary patency rate and the assisted primary patency rate were 97.7% and 100%, respectively. The entry of IV stents into the IVC was safe and had a very low incidence of thrombosis in the contralateral vein. Stenting less into the IVC increased the incidence of thrombosis in the ipsilateral vein, especially among thrombotic cases. Treatment of NIVLs using stent implantation had a better long-term patency rate. This principle plays an important guiding role in the endovascular therapy of IV lesions.


Iliac vein stenting Contralateral vein Endovascular therapy Thrombosis 



This work was supported by Science and Technology Program of Yangzhou, China (YZ2016063).

Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflict of interest.

Ethical approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

Informed consent

Informed consent was obtained from all individual participants included in the study.


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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2018

Authors and Affiliations

  • Xicheng Zhang
    • 1
    Email author
  • Yuanhu Jing
    • 1
  • Hongfei Sang
    • 2
  • Zhaolei Chen
    • 1
  • Yuan Sun
    • 1
  • Xiaoqiang Li
    • 2
  1. 1.Department of Vascular SurgeryThe Clinical Medical College of Yangzhou UniversityYangzhouChina
  2. 2.Department of Vascular SurgeryThe Second Affiliated Hospital of Soochow UniversitySoochowChina

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