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Russian Chemical Bulletin

, Volume 68, Issue 5, pp 1075–1080 | Cite as

Polysiloxane based on hydroxyl-containing monomer. Preparation, properties and biomedical application

  • T. S. Lyubova
  • N. S. Zakharycheva
  • E. A. Zakharychev
  • S. A. Lermontova
  • E. Yu. LadilinaEmail author
  • L. G. Klapshina
Full Article
  • 6 Downloads

Abstract

A method for synthesis of hyperbranched polysiloxane based on N-methyl-N-(2,3,4,5,6-pentahydroxyhexyl)-N’-(3-triethoxysilylpropyl)urea is proposed. In water, the polymer forms nanoparticles capable of holding low soluble luminophores (tetracyanotetraarylporphyrazines) due to non-covalent interaction. Intensively luminescent stable aqueous suspensions based on non-toxic siloxane nanoparticles can be used in bioimaging.

Key words

dynamic light scattering drug delivery luminescence nanoparticles polysiloxanes 

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Copyright information

© Springer Science+Business Media, Inc. 2019

Authors and Affiliations

  • T. S. Lyubova
    • 1
  • N. S. Zakharycheva
    • 2
  • E. A. Zakharychev
    • 2
  • S. A. Lermontova
    • 1
  • E. Yu. Ladilina
    • 1
    Email author
  • L. G. Klapshina
    • 1
  1. 1.Razuvaev Institute of Organometallic ChemistryRussian Academy of SciencesNizhni NovgorodRussian Federation
  2. 2.Lobachevsky State University of Nizhny NovgorodNizhny NovgorodRussian Federation

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