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Russian Chemical Bulletin

, Volume 68, Issue 5, pp 985–992 | Cite as

Comparative evaluation of antioxidant activity of 2-alkyl-4-methylphenols and their 6-n-octylaminomethyl derivatives

  • E. V. BuravlevEmail author
  • I. V. Fedorova
  • O. G. Shevchenko
Full Article

Abstract

A series of 2-alkyl-4-methyl-6-n-octylaminomethylphenols (where alkyl is methyl or tert-butyl group, or terpene substituent) was synthesized. A comparative evaluation of the antioxidant properties of the starting alkyl- and terpenylphenols and their Mannich bases was carried out using in vitro assays. Structural features providing high antioxidant activity of these compounds were revealed.

Key words

Schiff bases Mannich bases chelation ability antioxidant activity membrane-protective activity red blood cells oxidative hemolysis 

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Copyright information

© Springer Science+Business Media, Inc. 2019

Authors and Affiliations

  • E. V. Buravlev
    • 1
    Email author
  • I. V. Fedorova
    • 1
  • O. G. Shevchenko
    • 2
  1. 1.Institute of Chemistry, Komi Scientific CenterUral Branch of the Russian Academy of SciencesSyktyvkarRussian Federation
  2. 2.Institute of Biology, Komi Scientific CenterUral Branch of the Russian Academy of SciencesSyktyvkarRussian Federation

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