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Russian Chemical Bulletin

, Volume 68, Issue 5, pp 887–910 | Cite as

Benzofuroxans: their synthesis, properties, and biological activity

  • E. A. ChugunovaEmail author
  • A. S. Gazizov
  • A. R. Burilov
  • L. M. Yusupova
  • M. A. Pudovik
  • O. G. Sinyashin
Review

Abstract

The review provides a brief historical background for the establishment of structure of benzofuroxanes. Methods for their synthesis are summarized, and the chemical properties are described, which are splitted into two parts: reactions proceeding with a ring opening of the heterocycle, and those occuring with a participation of the isocyclic moiety. The biological activity of various representatives belonging to the benzofuroxan series is covered in details.

Key words

benzofuroxan “hybrid” compounds tautomerism Boulton—Katritzky rearrangement Beirut reaction biological activity 

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Copyright information

© Springer Science+Business Media, Inc. 2019

Authors and Affiliations

  • E. A. Chugunova
    • 1
    • 2
    Email author
  • A. S. Gazizov
    • 1
  • A. R. Burilov
    • 1
  • L. M. Yusupova
    • 3
  • M. A. Pudovik
    • 1
  • O. G. Sinyashin
    • 1
  1. 1.A. E. Arbuzov Institute of Organic and Physical ChemistryFederal Research Center “Kazan Scientific Center of the Russian Academy of Sciences”KazanRussian Federation
  2. 2.Kazan Federal UniversityKazanRussian Federation
  3. 3.Kazan National Research Technological UniversityKazanRussian Federation

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