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Russian Chemical Bulletin

, Volume 68, Issue 2, pp 405–410 | Cite as

Synthesis and physicochemical properties of the pectin complexes with Xymedon

  • S. T. MinzanovaEmail author
  • V. F. Mironov
  • A. V. Khabibullina
  • D. M. Arkhipova
  • L. G. Mironova
  • I. S. Ryzhkina
  • S. Yu. Sergeeva
  • L. I. Murtazina
  • F. R. Smolobochkina
  • V. A. Milyukov
Full Articles
  • 13 Downloads

Abstract

The formation of stable complexes of pectin polysaccharides with 1-(2-hydroxyethyl)-4,6- dimethyl-1,2-dihydropyrimidin-2-one (Xymedon drug) was shown by UV and IR spectro scopy, dynamic light scattering, and polarimetry. The stoichiometry of the complexes was determined, and their synthesis conditions were optimized. Specific features of the thermal decomposition of pectin and synthesized complexes with Xymedon were studied by the TG/DSC method. The results obtained allow one to substantially extend ranges of using Xymedon in medicine.

Key words

pectin Xymedon complexation 

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Copyright information

© Springer Science+Business Media, Inc. 2019

Authors and Affiliations

  • S. T. Minzanova
    • 1
    Email author
  • V. F. Mironov
    • 1
  • A. V. Khabibullina
    • 1
  • D. M. Arkhipova
    • 1
  • L. G. Mironova
    • 1
  • I. S. Ryzhkina
    • 1
  • S. Yu. Sergeeva
    • 1
  • L. I. Murtazina
    • 1
  • F. R. Smolobochkina
    • 1
  • V. A. Milyukov
    • 1
  1. 1.A. E. Arbuzov Institute of Organic and Physical ChemistryFederal Research Center “Kazan Scientific Center of the Russian Academy of Sciences,”KazanRussian Federation

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