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Russian Chemical Bulletin

, Volume 68, Issue 2, pp 365–373 | Cite as

Synthesis of new trichloromethyl- and alkoxy-substituted pyrido[2,3-d]pyrimidine derivatives

  • A. V. Komkov
  • T. V. Potapova
  • M. I. Zuev
  • S. V. BaraninEmail author
  • Yu. N. Bubnov
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  • 8 Downloads

Abstract

A series of new trichloromethyl- and alkoxy-substituted pyrido[2,3-d]pyrimidine derivatives were obtained from trichloromethyl-substituted pyrimidines with vicinal amino and acyl groups synthesized based on the reaction of trichloroacetonitrile with β-diketone diaminomethylidene derivatives.

Key words

trichloroacetonitlile α,α-diacyl ketene aminals N-acyl-α-acetyl ketene aminals amidines pyrimidines pyrido[2,3-d]pyrimidines 

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Copyright information

© Springer Science+Business Media, Inc. 2019

Authors and Affiliations

  • A. V. Komkov
    • 1
  • T. V. Potapova
    • 1
  • M. I. Zuev
    • 1
  • S. V. Baranin
    • 1
    Email author
  • Yu. N. Bubnov
    • 1
  1. 1.N. D. Zelinsky Institute of Organic ChemistryRussian Academy of SciencesMoscowRussian Federation

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