Russian Chemical Bulletin

, Volume 68, Issue 2, pp 328–333 | Cite as

Aggregation behavior and solubilization properties of 3-hydroxypiperidinium surfactants

  • A. B. MirgorodskayaEmail author
  • R. A. Kushnazarova
  • S. S. Lukashenko
  • L. Ya. Zakharova
Full Articles


Systematic data on the aggregation behavior of novel 3-hydroxypiperidinium surfactants in aqueous solutions were obtained. The ability of the surfactants to solubilize hydrophobic compounds, including the Orange OT dye and biologically active flavonoid quercetin, was characterized. The maximally achieved limiting content of these substances in micellar solutions of 3-hydroxypiperidinium surfactants is by two to three times higher than that in solutions of their non-functionalized analogs. The solubility of quercetin depends on the pH of the medium, and the highest effect observed on going from water to micellar solutions of the studied surfactants reaches two orders of magnitude.

Key words

surfactants aggregation solubilization drugs 


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Copyright information

© Springer Science+Business Media, Inc. 2019

Authors and Affiliations

  • A. B. Mirgorodskaya
    • 1
    Email author
  • R. A. Kushnazarova
    • 1
  • S. S. Lukashenko
    • 1
  • L. Ya. Zakharova
    • 1
  1. 1.A. E. Arbuzov Institute of Organic and Physical ChemistryFederal Research Center “Kazan Scientific Center of the Russian Academy of Sciences,”KazanRussian Federation

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