Sulfonic acid-functionalized poly(4-styrenesulfonic acid) mesoporous graphene oxide hybrid for one-pot preparation of coumarin-based pyrido[2,3-d]pyrimidine-dione derivatives

  • Mohammad Hosein SayahiEmail author
  • Saeed BahadorikhaliliEmail author
  • Seyyed Jafar Saghanezhad
  • Max A. Miller
  • Mohammad Mahdavi


Sulfonic acid-functionalized poly(4-styrenesulfonic acid) mesoporous graphene oxide hybrid (PSSA-MGO) is prepared by polymerization of 4-styrenesulfonic acid on the surface of mesoporous graphene oxide. The catalyst is fully characterized by several methods including Fourier-transform infrared spectroscopy, Brunauer–Emmett–Teller adsorption–desorption analysis, scanning and transmission electron microscopy. PSSA-MGO is used as an efficient acidic catalyst for the one-pot preparation of some novel chromenopyridopyrimidine-dione derivatives via the three-component reaction of 4-aminocoumarin, thiobarbituric acid and aromatic aldehydes. All the obtained products were also characterized. This synthetic procedure presents some advantages including an eco-friendly procedure, high yield of the products and recyclability of the catalyst.


Poly(4-styrenesulfonic acid) Mesoporous graphene oxide Pyridopyrimidinedione 4-aminocoumarin Multi-component reaction 



We gratefully acknowledge the support of this work by Payame Noor University (PNU).

Supplementary material

11164_2019_3962_MOESM1_ESM.pdf (704 kb)
Supplementary material 1 (PDF 704 kb)


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Copyright information

© Springer Nature B.V. 2019

Authors and Affiliations

  1. 1.Department of ChemistryPayame Noor University (PNU)TehranIran
  2. 2.School of Chemistry, College of ScienceUniversity of TehranTehranIran
  3. 3.ACECR-Production Technology Research InstituteAhvazIran
  4. 4.Polymer Chemistry Department, Ångström LaboratoryUppsala UniversityUppsalaSweden
  5. 5.Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences InstituteTehran University of Medical SciencesTehranIran

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