Research on Chemical Intermediates

, Volume 45, Issue 5, pp 2549–2563 | Cite as

Preparation and characterization of Fe3O4@Cu-β-CD as a hybrid magnetic catalyst for the synthesis of dihydropyrano[2,3-c]pyrazoles in H2O

  • Fatemeh Mirhashemi
  • Mohammad Ali AmrollahiEmail author


Fe3O4@Cu-β-CD is a hybrid composite with high catalytic activity. Easy separation with an external magnet and recyclability are the advantages of this catalyst. The magnetic composite was characterized by TEM, FE-SEM, XRD, EDS, VSM and FT-IR techniques. The result of the TEM analysis shows that the average size of the Fe3O4@Cu-β-CD composite is less than 80 nm. The catalyst was applied for the synthesis of dihydropyrano[2,3-c]pyrazole derivatives in water. Various dihydropyrano[2,3-c]pyrazole derivatives were prepared in high to excellent yields with short reaction times and high purity in aqueous medium.

Graphical abstract


Hybrid composite β-CD Dihydropyrano[2,3-c]pyrazoles Fe3O4@Cu-β-CD Inclusion complex 



The authors thank the Research Council of Yazd University for the financial support.


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Copyright information

© Springer Nature B.V. 2019

Authors and Affiliations

  1. 1.Department of Chemistry, College of ScienceYazd UniversityYazdIran

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