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Two novel fluorescent probes based on phenothiazine: synthesis and “naked-eye” colorimetric recognition of Hg2+

  • Chuane Wang
  • Lizhen Wang
  • Shimin Fang
  • Dawei Qin
  • Jianhua Zhou
  • Geng Yang
  • Shuangshuang Jin
  • Hongdong Duan
Article
  • 20 Downloads

Abstract

Two novel colorimetric and fluorescent probes 2-(1,3-dithiolanes)-10-ethyl phenothiazine (PHE–Ed) and 2-(1,3-dithianes)-10-ethyl phenothiazine (PHE–Pd) based on phenothiazine were successfully synthesized, and their structure was confirmed by NMR and high resolution mass spectra. Fluorescence investigations revealed that the synthesized probes could be used for the selective detection of Hg2+, which was accompanied with an obvious color change from colorless to light yellow. The applicable ability of the two probes was investigated by a series of competitive experiments, solid colorimetric experiments, and applied experiments, which proved that these probes showed high sensitivity and great potential to detect Hg2+ in environmental analysis systems. Furthermore, the detection mechanism of the probes was investigated by FT-IR spectra and NMR spectra, and the results indicated that the detection of Hg2+ was accomplished through the Hg2+-promoted deprotection of thioacetal.

Keywords

Phenothiazine 1,2-ethanedithiol 1,3-propanedithiol ICT fluorophore Naked-eye 

Notes

Acknowledgements

The work was supported by the Shandong Provincial Natural Science Foundation of China (ZR2016EMM13, ZR2017LC005, ZR2018PB007), the Major Science and Technology Innovation Project of Shandong Province (2018CXGC1107).

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Copyright information

© Springer Nature B.V. 2019

Authors and Affiliations

  • Chuane Wang
    • 1
  • Lizhen Wang
    • 2
  • Shimin Fang
    • 1
  • Dawei Qin
    • 1
  • Jianhua Zhou
    • 1
  • Geng Yang
    • 1
  • Shuangshuang Jin
    • 1
  • Hongdong Duan
    • 1
  1. 1.School of Chemistry and Pharmaceutical EngineeringQilu University of Technology, (Shandong Academy of Sciences)JinanChina
  2. 2.Biology InstituteQilu University of Technology (Shandong Academy of Sciences)JinanChina

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