Quality of Life Research

, Volume 28, Issue 5, pp 1349–1354 | Cite as

Gestational diabetes mellitus and quality of life during the third trimester of pregnancy

  • Kyriakos A. PantzartzisEmail author
  • Philip P. Manolopoulos
  • Stavroula A. Paschou
  • Kyriakos Kazakos
  • Kalliopi Kotsa
  • Dimitrios G. Goulis



The primary aim of this study was to investigate the effect of gestational diabetes mellitus (GDM) on the quality of life (QoL) of pregnant women during the third trimester of pregnancy. The secondary aim was to compare the QoL of pregnant women with GDM according to their therapeutic approach. This is the first study of this kind conducted in Greece.


A case-control study with 62 pregnant women (31 with GDM and 31 with uncomplicated pregnancy), during the third trimester of pregnancy. QoL and Health Related QoL were studied with the use of three questionnaires (EQ-5D-5L, WHOQOL-BREF and ADDQoL).


A decrease in the QoL was found in pregnant women with GDM compared with pregnant women with uncomplicated pregnancy (p < 0.05) regarding both social life and health scales. On the contrary, there was no difference in the QoL between pregnant women with GDM who followed different treatment approaches (diet or insulin).


The diagnosis of GDM is associated with a reduction in the QoL of pregnant women during the third trimester of pregnancy, while the type of treatment does not seem to further affect it. More studies should be conducted so that the modifiers of this association can be clarified.


Pregnancy Gestational diabetes Quality of life Third trimester 


Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflict of interest.

Ethical approval

All procedures performed in this study were in accordance with the ethical standards of the institutional research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

Informed consent

Informed consent was obtained from all individual participants included in the study.


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© Springer Nature Switzerland AG 2019

Authors and Affiliations

  1. 1.Department of Nursing, School of Occupational Health and WelfareAlexandrion Technological Educational Institute of ThessalonikiThessalonikiGreece
  2. 2.School of MedicineEuropean University CyprusNicosiaCyprus
  3. 3.Division of Endocrinology and Diabetes, “Aghia Sophia” Hospital, Medical SchoolNational and Kapodistrian University of AthensAthensGreece
  4. 4.Department of Endocrinology, Metabolism and Diabetes, First Department of Internal Medicine, Medical SchoolAristotle University of ThessalonikiThessalonikiGreece
  5. 5.Unit of Reproductive Endocrinology, First Department of Obstetrics and Gynecology, Medical SchoolAristotle University of ThessalonikiThessalonikiGreece

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