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Plant Foods for Human Nutrition

, Volume 74, Issue 4, pp 495–500 | Cite as

Spray-Dried Yerba Mate Extract Capsules: Clinical Evaluation and Antioxidant Potential in Healthy Individuals

  • Aline Minuzzi Becker
  • Heloisa Pamplona Cunha
  • Antônio Corrêa Lindenberg
  • Fernanda de Andrade
  • Tales de Carvalho
  • Brunna Cristina Bremer Boaventura
  • Edson Luiz da SilvaEmail author
Original Paper
  • 149 Downloads

Abstract

The aim of the present study was to evaluate the clinical effects and antioxidant potential of spray-dried yerba mate extract (SDME) capsules in healthy individuals. Fourteen healthy volunteers consumed three capsules of SDME three times daily. Measurements were carried out at the baseline and after 7, 30, and 60 days of SDME capsules intake. Electrocardiogram, hematological, urinary, and biochemical parameters analyzed remained within the normal values during all the study. SDME capsules ingestion increased significantly serum antioxidant capacity (after 7 and 30 days) and reduced glutathione values (after 7 and 60 days), and the superoxide dismutase (after 7, 30, and 60 days), catalase (after 7 and 30 days), and paraoxonase-1 activities (after 7 days); and decreased lipid hydroperoxides (after 30 and 60 days) and thiobarbituric acid reactive substances levels (after 7 and 30 days). No change was observed for glutathione peroxidase activity after SDME capsules intake. The present study showed that SDME capsules ingestion by healthy individuals did not promote clinical changes and promoted an increase of antioxidant biomarkers with a concomitant decrease of lipid peroxidation biomarkers in a short and prolonged manner.

Keywords

Ilex paraguariensis Capsules Bioactive compounds Oxidative stress Antioxidants Humans 

Abbreviations

CAT

Catalase

FRAP

Ferric reducing antioxidant potential

GPx

Glutathione peroxidase

GSH

Reduced glutathione

LOOH

Lipid hydroperoxides

SDME

Spray-dried yerba mate extract

SOD

Superoxide dismutase

TBARS

Thiobarbituric acid reactive substances

TEAC

Trolox equivalent antioxidant capacity

Notes

Acknowledgments

We are grateful to volunteers who participated in the study. The authors would like to thank Leao Alimentos e Bebidas Co. (Curitiba-PR, Brazil) for providing plant material. This study was financed in part by the Coordenação de Aperfeiçoamento de Pessoal de Nível Superior - Brasil (CAPES) - Finance Code 001.

Compliance with Ethical Standards

Conflict of Interest

The authors declare that there are no conflicts of interest.

Supplementary material

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Table S1 (DOCX 14 kb)
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Table S2 (DOCX 14 kb)
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Table S3 (DOCX 15 kb)
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Table S4 (DOCX 15 kb)

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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2019

Authors and Affiliations

  • Aline Minuzzi Becker
    • 1
  • Heloisa Pamplona Cunha
    • 1
  • Antônio Corrêa Lindenberg
    • 2
  • Fernanda de Andrade
    • 1
  • Tales de Carvalho
    • 3
  • Brunna Cristina Bremer Boaventura
    • 4
    • 5
  • Edson Luiz da Silva
    • 1
    • 2
    • 4
    Email author
  1. 1.Graduate Program in Pharmacy, Health Sciences CenterFederal University of Santa CatarinaFlorianópolisBrazil
  2. 2.Department of Clinical Analyses, Health Sciences CenterFederal University of Santa CatarinaFlorianópolisBrazil
  3. 3.Health Sciences and Sports Center, Center of Cardiology and Exercise MedicineState University of Santa CatarinaFlorianópolisBrazil
  4. 4.Graduate Program in Nutrition, Health Sciences CenterFederal University of Santa CatarinaFlorianópolisBrazil
  5. 5.Department of Nutrition, Health Sciences CenterFederal University of Santa CatarinaFlorianópolisBrazil

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