Advertisement

Beliefs about medicines in pregnancy: a survey using the beliefs about medicines questionnaire in Indonesia

  • Gesnita Nugraheni
  • Arie Sulistyarini
  • Elida ZairinaEmail author
Research Article
  • 47 Downloads

Abstract

Background Many studies examine the use of medicines among pregnant women, however few studies report the pregnant women’s belief for taking medication during pregnancy. Individual factors such as patients’ beliefs about their medications have been known to influence medication adherence. Objective This study aimed to examine beliefs about medicines among pregnant women in Indonesia and how these varied across pregnancy trimesters. Setting We conducted a cross-sectional survey of pregnant women who had regular visits at 63 community health centres in Surabaya, Indonesia. Methods Participants were approached while they were in the waiting room and were asked to complete the questionnaire. The survey package contained information about the study, an informed consent form, and the Beliefs about Medicines Questionnaire (BMQ). Main outcome measure Beliefs about medicines were assessed using the BMQ, which comprises four subscales: general-overuse, general-harm, specific-necessity, and specific-concern. Differences in medication beliefs between pregnancy trimesters were assessed using suitable statistical tests according to data normality. Results A total of 492 pregnant women completed the survey. The majority were aged 21–30 years (57.1%), housemakers (68.7%), and educated to high-school level (51.4%); 92.9% did not have any chronic diseases, and more than 90% took vitamins and/or supplements. The difference between Specific-Concern and Specific-Necessity scores was calculated for each participant, and more than half of the participants (59.6%) were thus classified as having negative beliefs about medications. In the first trimester of pregnancy, women’s beliefs about medication necessity were stronger than in the third trimester (p = 0.033). Conclusion Medication beliefs of pregnant women regarding their concerns and the necessity of medication taken in different trimesters of pregnancy were varied. The results of this study highlight the difference in medication beliefs during trimesters in pregnancy.

Keywords

Beliefs about medicine Indonesia Medicine Pregnancy Survey 

Notes

Acknowledgements

The authors thank the Ministry of Research and Technology and Higher Degree of Indonesia and the Faculty of Pharmacy at Universitas Airlangga for the support and facilities provided during the study. The authors also thank all of the staff at the primary health care centres in Surabaya for the study setting. The authors would also like to thank Ms. Leila Miftahun, Ms. Ayu Zulaicha, Ms. Eka Putri, Ms. Tarisa, and Ms. Mifta Nauli for their help in recruiting participants.

Funding

This study was supported by the Ministry of Research and Technology and Higher Degree of Indonesia.

Conflicts of interest

The authors declare no potential conflicts of interest.

References

  1. 1.
    World Health Organization. Adherence to long-term therapies: evidence for action. Geneva: World Health Organization; 2003.Google Scholar
  2. 2.
    Baggley A, Navioz Y, Maltepe C, Koren G, Einarson A. Determinants of women’s decision making on whether to treat nausea and vomiting of pregnancy pharmacologically. J Midwifery Womens Health. 2004;49(4):350–4.CrossRefGoogle Scholar
  3. 3.
    Briggs G, Freeman R, Yaffe SJ. Drugs in pregnancy and lactation. Philadelphia: Lippincott Williams & Willkins; 2011.Google Scholar
  4. 4.
    Twigg MJ, Lupattelli A, Nordeng H. Women’s beliefs about medication use during their pregnancy: a UK perspective. Inter J Clin Pharm. 2016;38:968–76.CrossRefGoogle Scholar
  5. 5.
    Seal F, Cave JA, Atkinson LL. Primary non-adherence of prescribed pharmaceutical treatments and interventions: an investigative review to improve quality in primary care. Qual Prim Care. 2017;25:344–59.Google Scholar
  6. 6.
    Sawicki E, Stewart K, Wong S, Leung L, Paul E, George J. Medication use for chronic health conditions by pregnant women attending an Australian maternity hospital. Aust N Z J Obstet Gynaecol. 2011;51:333–8.CrossRefGoogle Scholar
  7. 7.
    Duley L. The global impact of pre-eclampsia and eclampsia. Semin Perinatol. 2009;33:130–7.CrossRefGoogle Scholar
  8. 8.
    Smedberg J, Brathen M, Waka M, Jacobsen A, Gjerdalen G, Nordeng H. Medication use and drug-related problems among women at maternity wards-a cross-sectional study from two Norwegian hospitals. Eur J Clin Pharmacol. 2010;72:849–57.CrossRefGoogle Scholar
  9. 9.
    Lupattelli A, Spigset O, Nordeng H. Adherence to medication for chronic disorders during pregnancy: results from a multinational study. Int J Clin Pharm. 2014;36:145–53.CrossRefGoogle Scholar
  10. 10.
    Indonesian Ministry of Health, Peraturan Menteri Kesehatan No.74 Tahun 2016 tentang Standar Pelayanan Kefarmasian di Puskesmas, Jakarta. 2016.Google Scholar
  11. 11.
    Horne R, Weinman J, Hankins M. The beliefs about medicines questionnaire: the development and evaluation of a new method for assessing the cognitive representation of medication. Psychol Health. 1999;14:1–24.CrossRefGoogle Scholar
  12. 12.
    Dietl A, Cupisti S, Beckmann MW, Schwab M, Zollner U. Pregnancy and obstetrical outcomes in women over 40 years of age. Geburtshilfe Frauenheilkd. 2015;75:827–32.CrossRefGoogle Scholar
  13. 13.
    da Silva KDL, Fernandes FEM, de Lima Pessoa T, Lima SIVC, Oliveira AG, Martins RR. Prevalence and profile of adverse drug reactions in high-risk pregnancy: a cohort study. BMC Pregnancy Childbirth. 2019;19:199.CrossRefGoogle Scholar
  14. 14.
    Nordeng H, Koren G, Einarson A. Pregnant women’s beliefs about medications—a study among 866 Norwegian women. Ann Pharmacother. 2010;44:1478–84.CrossRefGoogle Scholar
  15. 15.
    Fakeye TO, Adisa R, Musa IE. Attitude and use of herbal medicines among pregnant women in Nigeria. BMC Complement Altern Med. 2009;9:53.CrossRefGoogle Scholar
  16. 16.
    Ahmed M, Hwang JH, Hasan MA, Han D. Herbal medicine use by pregnant women in Bangladesh: a cross-sectional study. BMC Complement Altern Med. 2018;18:333.CrossRefGoogle Scholar
  17. 17.
    Sachdeva P, Patel BG, Patel BK. Drug use in pregnancy; a point to ponder! Indian J Pharm Sci. 2009;71:1–7.CrossRefGoogle Scholar
  18. 18.
    Food and Drug Administration. Pregnancy and Lactation Labeling (Drugs) Final Rule. 2014.www.fda.gov/Drugs/DevelopmentApprovalProcess/DevelopmentResources/Labeling/ucm093307.htm Accessed 20 August 2018.
  19. 19.
    Hussar DA. Remington: the science and practice of pharmacy. In: Hendrickson R (ed) 21st ed. Lippincott Williams & Wilkins, Philadelphia, 2005; p. 1782–1795.Google Scholar

Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  1. 1.Department of Pharmacy Practice, Faculty of PharmacyUniversitas AirlanggaSurabayaIndonesia

Personalised recommendations