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International Journal of Clinical Pharmacy

, Volume 41, Issue 1, pp 141–150 | Cite as

Survey of outpatients’ use and needs of patient medicine information leaflets in Thailand

  • Supawinee Pongpunna
  • Thongchai Pratipanawatr
  • Narumol JarernsiripornkulEmail author
Research Article
  • 53 Downloads

Abstract

Background Patient information leaflets are important sources of medicine information. Regulations of patient information leaflet provision varies among country. Little is known regarding patients’ behavior and expectation on use of patient information leaflets. Objectives To explore patients’ use of either package inserts or patient information leaflets and to survey patients’ expectations and needs on use of patient information leaflets and their associated factors. Setting Two university hospitals in Thailand. Methods Cross-sectional study using self-administered questionnaires distributed to outpatients over a 3-month period. Participants were selected through systematic random sampling. Logistic regression was used for data analysis. Main outcome measure Patient use of medicine information. Visual Analogue Scale scores for patient needs and their expectation of knowledge gains from using patient information leaflets. Results The response rate was 77.0%. Most respondents had received package inserts (91.3%) with 59.4% reporting that they sometimes read them. While most respondents had not previously known about patient information leaflets (75.9%), 97.3% reported that patient information leaflets would be useful. Respondents scored their needs and expected knowledge gains after reading patient information leaflets as 9.68 ± 0.97 and 9.64 ± 0.99, respectively. Previous experience with package inserts was associated with increased patient need scores (p = 0.002) and higher expected knowledge gains from use of patient information leaflets (p = 0.037). In addition, patients who had not previously known about patient information leaflets had higher expectations of knowledge gains (p = 0.016). Conclusion Overall, patients showed good behavior on reading package inserts. Although many patients were not previously aware of patient information leaflets, they realized the importance. Hence, patient information leaflets should be developed and provided to Thai patients.

Keywords

Expectations Expected knowledge Medicine information Patient needs Package inserts Patient information leaflets Thailand 

Notes

Acknowledgements

We would like to express our thanks to all participants in this study and the staff at Srinagarind hospital and Queen Sirikit Heart Center who assisted in data collection.

Funding

This study received financial support from Graduate School, Khon Kaen University (Grant Number 59121110). The funding organization had no role in the design or conduct of the study.

Conflicts of interest

The authors declare no conflicts of interest.

References

  1. 1.
    Rubio JS, García-Delgado P, Iglésias-Ferreira P, Mateus-Santos H, Martínez-Martínez F, Rubio JS, et al. Measurement of patients’ knowledge of their medication in community pharmacies in Portugal. Cien Saude Colet. 2015;20:219–28.CrossRefGoogle Scholar
  2. 2.
    Burgener AM. Enhancing communication to improve patient safety and to increase patient satisfaction. Health Care Manag. 2017;36:238–43.Google Scholar
  3. 3.
    Krska J, Morecroft CW. Patients’ use of information about medicine side effects in relation to experiences of suspected adverse drug reactions: a cross-sectional survey in medical in-patients. Drug Saf. 2013;36:673–80.CrossRefGoogle Scholar
  4. 4.
    Gibbs S, Waters WE, George CF. Prescription information leaflets: a national survey. J R Soc Med. 1990;83:292–7.CrossRefGoogle Scholar
  5. 5.
    Raynor DK, Savage I, Knapp P, Henley J. We are the experts: people with asthma talk about their medicine information needs. Patient Educ Couns. 2004;53:167–74.CrossRefGoogle Scholar
  6. 6.
    Ziegler DK, Mosier MC, Buenaver M, Okuyemi K. How much information about adverse effects of medication do patients want from physicians? Arch Intern Med. 2001;161:706–13.CrossRefGoogle Scholar
  7. 7.
    Jarernsiripornkul N, Chaipichit N, Chumworathayi P, Krska J. Management for improving patients’ knowledge and understanding about drug allergy. Pharm Pract (Granada). 2015;13:513.CrossRefGoogle Scholar
  8. 8.
    European Medicines Agency. Information on benefit-risk of medicines: patients’, consumers’ and healthcare professionals’ expectations. London; 2009. http://www.emea.europa.eu.
  9. 9.
    Hill J, Bird H. The development and evaluation of a drug information leaflet for patients with rheumatoid arthritis. Rheumatology (Oxford). 2003;42:66–70.CrossRefGoogle Scholar
  10. 10.
    Kenny T, Wilson RG, Purves IN, Clark J, Newton LD, Newton DP, et al. A PIL for every ill? Patient information leaflets (PILs): a review of past, present and future use. Fam Pract. 1998;15:471–9.CrossRefGoogle Scholar
  11. 11.
    Kessels RP. Patients’ memory for medical information. J R Soc Med. 2003;96:219–22.Google Scholar
  12. 12.
    Boyle CM. Difference between patients’ and doctors’ interpretation of some common medical terms. Br Med J. 1970;2:286–9.CrossRefGoogle Scholar
  13. 13.
    Gibbs S, Waters W, George C. The benefits of prescription information leaflets (2). Br J Clin Pharmacol. 1989;28:345–51.CrossRefGoogle Scholar
  14. 14.
    Sustersic M, Jeannet E, Cozon-Rein L, Maréchaux F, Genty C, Foote A, et al. Impact of information leaflets on behavior of patients with gastroenteritis or tonsillitis: a cluster randomized trial in French primary care. J Gen Intern Med. 2013;28:25–31.CrossRefGoogle Scholar
  15. 15.
    Gotsch AR, Liguori S. Knowledge, attitude, and compliance dimensions of antibiotic therapy with PPIs: a community pharmacy-based study. Med Care. 1982;20:581–95.CrossRefGoogle Scholar
  16. 16.
    Adepu R, Swamy MK. Development and evaluation of patient information leaflets (PIL) usefulness. Indian J Pharm Sci. 2012;74:174–8.CrossRefGoogle Scholar
  17. 17.
    Phueanpinit P, Pongwecharak J, Krska J, Jarernsiripornkul N. Medicine information leaflets for non-steroidal anti-inflammatory drugs in Thailand. Int J Clin Pharm. 2016;38:25–9.CrossRefGoogle Scholar
  18. 18.
    Raynor DKT, Svarstad B, Knapp P, Aslani P, Rogers MB, Koo M, et al. Consumer medication information in the United States, Europe, and Australia: a comparative evaluation. J Am Pharm Assoc. 2007;47:717–726a.CrossRefGoogle Scholar
  19. 19.
    Garner M, Ning ZM, Francis J, Mark Garner C. A framework for the evaluation of patient information leaflets. Health Expect. 2011;15:283–94.CrossRefGoogle Scholar
  20. 20.
    Hamrosi KK, Aslani P, Raynor DK. Beyond needs and expectations: Identifying the barriers and facilitators to written medicine information provision and use in Australia. Health Expect. 2014;17:220–31.CrossRefGoogle Scholar
  21. 21.
    Turner RC, Carlson L. Indexes of item-objective congruence for multidimensional items. Int J Test. 2003;3:163–71.CrossRefGoogle Scholar
  22. 22.
  23. 23.
    Raynor D, Silcock J, Knapp P, Edmondson H. How do patients use medicine information leaflets in the UK? Int J Pharm Pract. 2007;15:209–18.CrossRefGoogle Scholar
  24. 24.
    Sweileh WM, Zeid AN, Jaradat NA. Drug informational value of patient package insert (PPI): a sample study in Palestine. IUG J Nat Stud. 2004;12:59–68.Google Scholar
  25. 25.
    Van Haecht CHM, Vander Stichele R, De Backer G, Bogaert MG. Impact of patient package inserts on patients’ satisfaction, adverse drug reactions and risk perception: the case of nsaids for posttraumatic pain relief. Patient Educ Couns. 1991;17:205–15.CrossRefGoogle Scholar
  26. 26.
    Asbury N, Walshe A. Involving women with breast cancer in the development of a patient information leaflet for anticipatory nausea and vomiting. Eur J Oncol Nurs. 2005;9:33–43.CrossRefGoogle Scholar
  27. 27.
    Koo MM, Krass I, Aslani P, Guzmàn WM, Le Duff M. Factors influencing consumer use of written drug information. Ann Pharmacother. 2003;37:259–67.CrossRefGoogle Scholar
  28. 28.
    Raynor DKT, Blenkinsopp A, Knapp P, Grime J, Nicolson DJ, Pollock K, et al. A systematic review of quantitative and qualitative research on the role and effectiveness of written information available to patients about individual medicines. Health Technol Assess (Rockv). 2007;11:1–160.Google Scholar
  29. 29.
    Fuchs J, Hippius M, Schaefer M. A survey of package inserts use by patients. Hosp Pharm Eur. 2005;21:29–31.Google Scholar
  30. 30.
    Raynor DK, Knapp P. Do patients see, read and retain the new mandatory medicines information leaflets? Pharm J. 2000;264:268–70.Google Scholar
  31. 31.
    Aslani P, Hamrosi K, Feletto E, Raynor DT, Knapp P, Hughes J, et al. Investigating Consumer Medicine Information (I-CMI) Project. 2012.Google Scholar
  32. 32.
    Burapadaja S, Tantipathananandh P, Sirithunyalug B. Consumer’ s opinions on reading a medicine leaflet. Chiang Mai Univ J. 2004;3:155–67.Google Scholar
  33. 33.
    Kuntz JL, Safford MM, Singh JA, Phansalkar S, Slight SP, Her QL, et al. Patient-centered interventions to improve medication management and adherence: a qualitative review of research findings. Patient Educ Couns. 2014;97:310–26.CrossRefGoogle Scholar
  34. 34.
    Schwappach DLB, Mülders V, Simic D, Wilm S, Thürmann PA. Is less more? Patients’ preferences for drug information leaflets. Pharmacoepidemiol Drug Saf. 2011;20:987–95.Google Scholar
  35. 35.
    Ekedahl A, Hoffmann M. Patients’ information on their prescribed current treatment. J Pharm Health Serv Res. 2012;3:79–84.CrossRefGoogle Scholar
  36. 36.
    Jarernsiripornkul N, Phueanpinit P, Pongwecharak J, Krska J. Experiences of and attitudes towards receiving information about non-steroidal anti-inflammatory drugs: a cross-sectional survey of patients in Thailand. Expert Opin Drug Saf. 2016;15:417–26.CrossRefGoogle Scholar
  37. 37.
    Fuchs J, Banow S, Görbert N, Hippius M. Europharm pharmind importance of package insert information in the European Union Medicinal and pharmaceutical experts questioning results. 2005.Google Scholar

Copyright information

© Springer Nature Switzerland AG 2018

Authors and Affiliations

  1. 1.Division of Clinical Pharmacy, Faculty of Pharmaceutical SciencesKhon Kaen UniversityKhon KaenThailand
  2. 2.Department of Medicine, Faculty of MedicineKhon Kaen UniversityKhon KaenThailand

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