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International Journal of Clinical Pharmacy

, Volume 40, Issue 3, pp 642–649 | Cite as

Development and psychometrics of a short-form pharmaceutical care-specific measure for quality of life

  • Phantipa SakthongEmail author
  • Nontapat Sonsa-ardjit
  • Pattarin Sukarnjanaset
  • Wipaporn Munpan
  • Todsaporn Sangthonganotai
Research Article
  • 113 Downloads

Abstract

Background The validated patient-reported outcomes measure of pharmaceutical therapy for quality of life (PROMPT-QoL) contains 43-items, and can be too lengthy for some applications. Objectives To develop a brief version called the PROMPT, and test its psychometric properties. Setting Four public hospitals in Bangkok, Thailand. Method Secondary analysis of three databases used to develop and evaluate the original PROMPT-QoL. Items for the short-form PROMPT were selected based on expert and patient evaluations of content and importance, and lack of redundancy. All domains of the original version are represented in the PROMPT. Main outcome measures Psychometric properties (internal consistency and test–retest reliability, criterion, convergent and discriminant validity, and responsiveness), and indicators of practicality (e.g., administration time, missing data). Results Analyses of the PROMPT and its domain subscales demonstrated good internal consistency and fair-to-excellent test–retest reliability. Correlations between the original and short-form, overall and by domain, were high. Expectations for convergent and discriminant validity were met as correlations between the PROMPT and generic health-related quality of life measures (WHOQoL-BREF domains and summary scores of the SF-12v2) were modest (< 0.40). Based on data from a trial of pharmaceutical care, the PROMPT short-form was very responsive to reductions in medication related problems. Administration time for the PROMPT is estimated to be about 5 min, and across all datasets used, no missing data were found amongst the 16 items of the PROMPT. Conclusion The 16-item PROMPT appears to be a practical, reliable, valid, and responsive instrument to identify patient’s drug-related needs and to assess the humanistic impact of patient-centered pharmaceutical care.

Keywords

Patient-reported outcomes Pharmaceutical care PROMPT-QOL Psychometrics Quality of life Thailand 

Notes

Acknowledgements

This study was funded by Thailand Research Fund, Chulalongkorn University and Faculty of Pharmaceutical Sciences, Chulalongkorn University (Grant Number: RSA 5580035). Part of this study was presented as a poster at 24th Annual Conference of International Society of Quality of Life Research in Philadelphia, U.S.A., during October 18–21, 2017. The authors would like to thank all patients for their participation in the study and the hospital staff for assistance with the data collection. The authors also thank Professor Cynthia R. Gross for her advice and helping edit the manuscript.

Funding

This study was funded by Thailand Research Fund, Chulalongkorn University and Faculty of Pharmaceutical Sciences, Chulalongkorn University (Grant No. RSA 5580035).

Conflicts of interest

None of the authors has any conflict of interest to declare.

Supplementary material

11096_2018_638_MOESM1_ESM.docx (21 kb)
Supplementary material 1 (DOCX 20 kb)

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Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  • Phantipa Sakthong
    • 1
    Email author
  • Nontapat Sonsa-ardjit
    • 2
  • Pattarin Sukarnjanaset
    • 3
  • Wipaporn Munpan
    • 4
  • Todsaporn Sangthonganotai
    • 5
  1. 1.Department of Pharmacy Practice, Faculty of Pharmaceutical SciencesChulalongkorn UniversityBangkokThailand
  2. 2.Pharmacy UnitKing Chulalongkorn Memorial HospitalBangkokThailand
  3. 3.Department of Pharmaceutical Care, Faculty of Pharmaceutical SciencesRangsit UniversityPathumthaniThailand
  4. 4.Pharmacy UnitPhramongkutklao HospitalBangkokThailand
  5. 5.Pharmacy UnitKlang HospitalBangkokThailand

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