Advertisement

International Journal of Clinical Pharmacy

, Volume 36, Issue 1, pp 4–7 | Cite as

What is patient adherence? A terminology overview

  • Rana Ahmed
  • Parisa AslaniEmail author
Commentary

Abstract

It is well known that patient adherence to appropriately prescribed medications is essential for treatment efficacy and positive therapeutic outcomes. It is also understood that patients who are prescribed medications do not necessarily take them as prescribed. Indeed, variation in patients' medication-taking is an age old conundrum which remains the focus of much interest amongst researchers and clinicians owing to its far-reaching consequences. Despite the extensive adherence-related research over the last four decades and a recent surge in this field, there remains a lack of uniformity in the terminology used to describe adherence and its related concepts. In turn, it is often difficult to conduct comparisons between adherence-related studies, which may be associated with the non-cumulative nature of work in this field. The purpose of this commentary is to provide an overview of key terminology relating to the field of adherence research.

Keywords

Concordance Medication adherence Patient compliance Persistence Terminology 

Notes

Funding

None.

Conflicts of interest

None.

References

  1. 1.
    Adams F. Genuine works of Hippocrates. Melbourne: Krieger Publishing; 1972.Google Scholar
  2. 2.
    World Health Organization. Adherence to long-term therapies: evidence for action. Geneva: World Health Organization; 2003.Google Scholar
  3. 3.
    Fredericks EM, Magee JC, Opipari-Arrigan L, Shieck V, Well A, Lopez MJ. Adherence and health-related quality of life in adolescent liver transplant recipients. Pediatr Transplant. 2008;12(3):289–99.PubMedCrossRefGoogle Scholar
  4. 4.
    Drotar D, Greenley RN, Demeter CA, et al. Adherence to pharmacological treatment for juvenile bipolar disorder. J Am Acad Child Adol Psychiatry. 2007;46(7):831–9.CrossRefGoogle Scholar
  5. 5.
    Buckley P. Adherence to mental health treatment. New York: Oxford University Press; 2009.Google Scholar
  6. 6.
    Osterberg L, Blaschke T. Adherence to medication. N Engl J Med. 2005;353(5):487–97.PubMedCrossRefGoogle Scholar
  7. 7.
    Lehane E, Mccarthy G. Medication non-adherence–exploring the conceptual mire. Int J Nurs Pract. 2009;15(1):25–31.PubMedCrossRefGoogle Scholar
  8. 8.
    Chacko A, Newcorn JH, Feirsen N, Uderman JZ. Improving medication adherence in chronic pediatric health conditions: a focus on ADHD in youth. Curr Pharm Des. 2010;16(22):2416–23.PubMedCrossRefGoogle Scholar
  9. 9.
    Vrijens B, De Geest S, Hughes DA, et al. A new taxonomy for describing and defining adherence to medications. Brit J Clin Pharm. 2012;73(5):691–705.PubMedCrossRefGoogle Scholar
  10. 10.
    Bissonnette JM. Adherence: a concept analysis. J Adv Nurs. 2008;63(6):634–43.PubMedCrossRefGoogle Scholar
  11. 11.
    Blackburn DF, Swidrovich J, Lemstra M. Non-adherence in type 2 diabetes: practical considerations for interpreting the literature. Patient Prefer Adherence. 2013;7:183–9.PubMedCentralPubMedCrossRefGoogle Scholar
  12. 12.
    Sackett DL, Haynes RB. Compliance with therapeutic regimens. Baltimore: The Johns Hopkins University Press; 1976.Google Scholar
  13. 13.
    Hughes CM. Medication non-adherence in the elderly: how big is the problem? Drugs Aging. 2004;21:793–811.PubMedCrossRefGoogle Scholar
  14. 14.
    Blackwell B. From compliance to alliance. A quarter century of research. Neth J Med. 1996;48:140–9.PubMedGoogle Scholar
  15. 15.
    Segal JZ. Compliance to concordance: a critical view. J Med Humanit. 2007;28:81–96.PubMedCrossRefGoogle Scholar
  16. 16.
    National Heart Foundation of Australia. Improving adherence in cardiovascular care. A toolkit for health professionals. Melbourne: National Heart Foundation of Australia; 2011.Google Scholar
  17. 17.
    Cramer JA, Roy A, Burrell A, et al. Medication compliance and persistence: terminology and definitions. Value Health. 2008;11(1):44–7.PubMedCrossRefGoogle Scholar
  18. 18.
    Ascertaining barriers for compliance (ABC) project team. ABC project. [Internet]. [Place unknown]: ABC project; c2010–2012 (2013). Available from: http://abcproject.eu/.
  19. 19.
    Caisley H, Muller U. Adherence to medication in adults with attention deficit hyperactivity disorder and pro re nata dosing of psychostimulants: a systematic review. Eur Psychiatry. 2012;27(5):343–9.PubMedCrossRefGoogle Scholar
  20. 20.
    Nunes V, Neilson J, O’Flynn N, et al. Clinical guidelines and evidence review for medicines adherence: involving patients in decisions about prescribed medicines and supporting adherence. London: National Collaborating Centre for Primary Care and Royal College of General Practitioners; 2009.Google Scholar
  21. 21.
    Robinson JH, Callister LC, Berry JA, Dearing KA. Patient-centered care and adherence: definitions and applications to improve outcomes. J Am Acad Nurs Pract. 2008;20(12):600–7.CrossRefGoogle Scholar
  22. 22.
    Institute of Medicine. Envisioning the national health care quality report. [Internet]. Washington D.C. (USA): Institute of Medicine; c2013 (2013). Available from: http://www.nap.edu/openbook.php?record_id=10073&page=7.

Copyright information

© Koninklijke Nederlandse Maatschappij ter bevordering der Pharmacie 2013

Authors and Affiliations

  1. 1.The University of SydneySydneyAustralia

Personalised recommendations