International Journal of Clinical Pharmacy

, Volume 35, Issue 5, pp 677–682 | Cite as

Potentially inappropriate prescribing among older residents in a geriatric hospital in Israel

  • Dvora FrankenthalEmail author
  • Yaffa Lerman
  • Edward Kalendaryev
  • Yehuda Lerman
Short Research Report


Background STOPP/START (“screening tool of older persons potentially inappropriate prescriptions”/“screening tool to alert doctors to right treatment”) criteria were formulated to identify potentially inappropriate prescriptions (PIP) and potential prescription omissions (PPO) in older people. Objective To determine the prevalence of PIP and PPO using STOPP/START criteria and to identify associated risk factors. Method Data were prospectively collected from 382 residents’ records in an Israeli geriatric hospital. The study population included subjects ≥65 years of age who were taking at least one medication. Data on demographics, medical histories, current diagnoses, current medications and biochemistry results were collected and analyzed. STOPP/START criteria were applied to each medical file. Results A total of 359 residents comprised the study group (mean age [±SD] 82.7 ± 8.7, 66.6 % females). STOPP identified 430 instances of PIP in 243 (67.7 %) residents, and START identified 151 PPO in 122 (34 %) residents. The number of medications (OR: 1.2, 95 % CI 1.11–1.3), falls (OR: 1.16, 95 % CI 1.021–1.32) and hospitalizations (OR: 1.25, 95 % CI 1.025–1.53) were identified as predictors for STOPP-defined PIP. The Charlson Comorbidity Index (OR: 1.4, 95 % CI 1.17–1.7) was associated with START-defined PPO. Conclusion A high prevalence of PIP/PPO was found among geriatric patients and was associated with number of medications, falls, hospitalizations and Charlson Comorbidity Index score.


Elderly Israel Nursing homes Screening tools START criteria STOPP criteria 



We would like to thank Keshet Association for the Elderly in Tel-Aviv-Yaffo for supporting this project and the staff of “Givat Hashlosha” geriatric hospital for their valuable assistance. We would also like to thank Ariella Herskovitz from Wolfson Medical Center, for her help in this project.


This work was supported partly by a research grant from Keshet Association for the Elderly in Tel-Aviv-Yaffo. The Keshet Association played no role in the design, execution, analysis and interpretation of data.

Conflicts of interest



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Copyright information

© Springer Science+Business Media Dordrecht 2013

Authors and Affiliations

  • Dvora Frankenthal
    • 1
    Email author
  • Yaffa Lerman
    • 2
  • Edward Kalendaryev
    • 3
  • Yehuda Lerman
    • 1
  1. 1.School of Public Health, Sackler Faculty of MedicineTel Aviv UniversityTel AvivIsrael
  2. 2.Geriatric DivisionTel Aviv Medical CenterTel AvivIsrael
  3. 3.“Givat Hashlosha” Geriatric HospitalPetach TiqvaIsrael

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