Pharmacy World and Science

, Volume 28, Issue 5, pp 302–308 | Cite as

Pharmaceutical care and its relationship to prescribing behaviour of general practitioners

  • Paul E. M. MuijrersEmail author
  • Richard P. T. M. Grol
  • Jildou Sijbrandij
  • Rob Janknegt
  • J. André Knottnerus
Research Article



To study the correlation between pharmaceutical care and prescribing routines of general practitioners (GPs).


Cross-sectional study; 201 pharmacies, 408 general practices, The Netherlands, 2000/2001. The variation in prescribing behaviour was characterised using 20 validated prescribing indicators based on general practice guidelines. The general construct ‘adherence to guidelines’ served as the dependent variable and was formed by summing the scores of the prescribing indicators. Four possible determinants of the variation were determined on the basis of survey questions: the construct ‘the pharmacist’s attitude towards pharmaceutical care’, and three partial constructs derived from the pharmacist’s care-providing function: the care for the individual patient, the cooperation with general practitioners and the registration of the care provided. A multiple linear regression analysis was then performed.

Main outcome measure

The weighted score for the prescribing indicators.


The weighted average score for the prescribing indicators was 65% (SD 3.7). The response rate to the survey was 71%. The pharmacist’s attitude to pharmaceutical care, as well as the degree to which the pharmacist provided care for the individual patient, the degree to which he cooperated with the general practitioner and the degree to which he registered the care provided were not correlated with the ‘adherence to guidelines’ by the general practitioner with whom the pharmacist frequently cooperated.


Variations between general practitioners in the quality of prescribing, as measured by their adherence to guidelines, were not correlated with pharmaceutical care by the pharmacist with whom they cooperated on a day-to-day basis.


Cooperation General practitioner Indicators Pharmacist Pharmaceutical care Pharmacotherapy Prescribing indicators Prescribing quality The Netherlands 



We thank the community pharmacists who participated in this study.

Funding: Royal Dutch Association for the Advancement of Pharmacy (KNMP) and CZ health insurance company.


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Copyright information

© Springer Science+Business Media B.V. 2006

Authors and Affiliations

  • Paul E. M. Muijrers
    • 1
    Email author
  • Richard P. T. M. Grol
    • 2
    • 3
  • Jildou Sijbrandij
    • 4
  • Rob Janknegt
    • 5
  • J. André Knottnerus
    • 6
  1. 1.Division HealthcareCZ Health Insurance CompanySittardThe Netherlands
  2. 2.Centre for Quality of Care Research (WOK)Maastricht UniversityMaastrichtThe Netherlands
  3. 3.University of NijmegenNijmegenThe Netherlands
  4. 4.Centre for Data and Information ManagementMaastricht UniversityMaastrichtThe Netherlands
  5. 5.Department of Clinical Pharmacy and ToxicologyMaasland HospitalSittardThe Netherlands
  6. 6.Netherlands School of Primary Care ResearchMaastricht UniversityMaastrichtThe Netherlands

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