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Pharmaceutical Chemistry Journal

, Volume 52, Issue 10, pp 865–867 | Cite as

Kinetics of One-Step Mepivacaine Synthesis on Polymers Containing Pd-Nanoparticles

  • M. G. AbdullaevEmail author
DRUG SYNTHESIS METHODS AND MANUFACTURING TECHNOLOGY
  • 39 Downloads

The kinetic factors influencing the hydroacylation of 2,6-dimethylnitrobenzene in the presence of Pd nanoparticles bound to anion exchangers were studied. A general scheme for catalytic synthesis of mepivacaine was proposed based on the obtained kinetic data. The one-step synthesis of mepivacaine was demonstrated to be efficient on various Pd-containing polymer catalysts.

Keywords

kinetics synthesis hydroacylation mepivacaine polymers containing Pd-nanoparticles 

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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2019

Authors and Affiliations

  1. 1.Dagestan State UniversityMakhachkalaRussia

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