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Using a Molecular Sensor Array with Colorimetric Detection to Identify Active Ingredients in Drug Formulations

  • A. A. ChaplenkoEmail author
  • O. V. Monogarova
  • K. V. Oskolok
STRUCTURE OF CHEMICAL COMPOUNDS, METHODS OF ANALYSIS AND PROCESS CONTROL
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A method for multiplex digital colorimetric qualitative analysis of nonsteroidal anti-inflammatory drugs (meloxicam, acetylsalicylic acid and its metabolites, paracetamol), β-adrenoblockers (carvedilol), secretolytics (bromhexine), fluoroquinolones (ofloxacin), metabolic stimulants (meldonium dihydrate), etc., was developed. The molecular chip operating efficiency was confirmed by verifying the authenticity of >40 medicinal substances. The proposed universal approach was new in principle and could be used for pharmaceutical quality control.

Keywords

molecular sensor digital colorimetry active ingredient medicine drug substance 

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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2019

Authors and Affiliations

  • A. A. Chaplenko
    • 1
    Email author
  • O. V. Monogarova
    • 1
  • K. V. Oskolok
    • 1
  1. 1.Department of ChemistryM. V. Lomonosov Moscow State UniversityMoscowRussia

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