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Quantitative UV-Spectrophotometric Determination of Ribavirin

  • K. I. Kienskaya
  • E. V. Il’yushenko
  • M. V. SardushkinEmail author
  • N. Yu. Guznova
  • T. Yu. Koldaeva
  • A. M. Kusmaev
  • R. R. Ibragimova
  • I. A. Belova
  • A. V. Kukharenko
  • L. I. Shaposhnikova
  • O. V. Zav’yalova
  • G. V. Avramenko
STRUCTURE OF CHEMICAL COMPOUNDS, METHOD OF ANALYSIS AND PROCESS CONTROL
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A quantitative UV-spectrophotometric method for determining ribavirin was proposed. The method was demonstrated to be suitable in validation tests. Spectrophotometric determination of ribavirin in tablets was demonstrated to be possible.

Keywords

UV spectrophotometry ribavirin 

Notes

Acknowledgments

The work was financially supported by D. I. Mendeleev UCTR, Project Nos. 003-2018 and 013-2018.

Equipment at the Industrial Biotechnologies Common Use Center, Basic Biotechnology Principles Federal Research Center, Russian Academy of Sciences, was used for the research.

We express our sincere thanks to Profs. V. V. Kuznetsov (Department of Analytical Chemistry), V. P. Perevalov (Department of Fine Organic Synthesis and Dye Chemistry), and Yu. I. Smushkevich (Department of Organic Chemistry), D. I. Mendeleev UCTR, for discussions and assistance in interpreting the experimental results and to Senior Scientist V. V. Shubin, A. N. Bakh Biochemistry Institute, for assistance with the spectral studies and processing the obtained results.

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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2019

Authors and Affiliations

  • K. I. Kienskaya
    • 1
  • E. V. Il’yushenko
    • 1
  • M. V. Sardushkin
    • 1
    Email author
  • N. Yu. Guznova
    • 2
  • T. Yu. Koldaeva
    • 1
  • A. M. Kusmaev
    • 1
  • R. R. Ibragimova
    • 1
  • I. A. Belova
    • 1
  • A. V. Kukharenko
    • 1
  • L. I. Shaposhnikova
    • 1
  • O. V. Zav’yalova
    • 3
  • G. V. Avramenko
    • 1
  1. 1.D. I. Mendeleev University of Chemical Technology of RussiaMoscowRussia
  2. 2.Polyclinica Virmed Ltd.TulaRussia
  3. 3.Collegium MedicumNicolaus Copernicus University in Torun’BydgoszczPoland

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