3D control stretched length of lambda-phage WLC DNA molecule by nonlinear optical tweezers

  • Thang Nguyen ManhEmail author
  • Quy Ho Quang
  • Thanh Thai Doan
  • Tuan Doan Quoc
  • Viet Do Thanh
  • Khoa Doan Quoc


In this paper, the general Langevin equations of motion for the polystyrene bead linked to the lambda-phage worm-like chain DNA molecule embedded in the fluid under the nonlinear optical tweezers is derived in 3D space. Using the finite difference method, the dynamical properties of the bead trapped by the nonlinear optical tweezers using a thin layer of Acid Blue 29 are numerically studied. Results in, the stretched length of the lambda-phage worm-like chain DNA molecule can be controlled in 3D space by finely tuning of the laser power.


Lasers Instruments Measurement and metrology Nonlinear optics Optical devices Biophysics 



This research is funded by Vietnam National Foundation for Science and Technology Development (NAFOSTED) under Grant Number 103.03-2018.342.


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Authors and Affiliations

  1. 1.Academy of Military Science and TechnologyHanoiVietnam
  2. 2.Ho Chi Minh City University of Food IndustryHo Chi Minh CityVietnam
  3. 3.Duy Tan UniversityDa NangVietnam

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