Fabrication of highly fluorescent multiple Fe3O4 nanoparticles core-silica shell nanoparticles

  • Wongyun Byoun
  • Moongyu Jang
  • Hyojong YooEmail author
Research Paper


The synthesis of hybrid nanoparticles with multiple functions from the economical and scalable perspective is an important issue in nanoparticle engineering. Herein, we report a representative example of multi-functional nanosystems simultaneously possessing fluorescence and magnetism as well as the excellent structural properties of nanosilica. Highly fluorescent multiple Fe3O4 nanoparticles core-silica shell nanoparticles (FL multi-Fe3O4@SiO2 NPs) are successfully synthesized and fully characterized. The multiple Fe3O4 nanoparticles can be uniformly and collectively encapsulated within a silica matrix using a reverse microemulsion (RM) method. Fluorescent dyes are successfully functionalized through the sequential hydrolysis and condensation of tetraethylorthosilicate (TEOS) and 3-(aminopropyl) triethoxysilane (APTES). Both organic (fluorescein) and inorganic (Rubpy) dyes can be used to generate the FL multi-Fe3O4@SiO2 NPs. These synthetic paradigms for multi-functional nanoparticles can significantly facilitate the fabrications of unique nanomaterials widely applied in a variety of areas.

Graphical abstract


Multi-functional nanosystem Core-shell nanoparticle Fluorescent nanosilica Magnetic property Iron oxide 



This work was supported by the Hallym Leading Research Group Support Program of 2017 (HRF-LGR-2017-0001).

Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflict of interest.

Supplementary material

11051_2018_4445_MOESM1_ESM.docx (1.1 mb)
ESM 1 (DOCX 1103 kb)


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© Springer Nature B.V. 2018

Authors and Affiliations

  1. 1.Department of ChemistryHallym UniversityChuncheonRepublic of Korea
  2. 2.School of Nano Convergence TechnologyHallym UniversityChuncheonRepublic of Korea

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