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Changing Concepts and Current Definition of Majocchi’s Granuloma

  • Murat Durdu
  • Hazal Kandemir
  • Macit IlkitEmail author
  • G. Sybren de Hoog
Original Article
  • 31 Downloads

Abstract

Dermatophytic granuloma characterized by perifollicular granulomatous inflammation was first described by Domenico Majocchi and was later named after him, Majocchi’s granuloma (MG). Although the initial description was related to a dermatophyte Trichophyton tonsurans, later reports linked MG to non-dermatophytes (Phoma, Aspergillus, Malbranchea), which led to a confusion of disease patterns caused by cutaneous pathogens and general opportunistic microorganisms. Furthermore, several causative agents of MG described in the literature were not confirmed as such. Our review addressed the following aspects: (1) significance of histopathological finding for MG diagnosis, (2) dermatophytes as exclusive agents of MG, (3) spectrum of etiological agents causing different types of invasive dermatophytic infections, and (4) treatment options.

Keywords

Dermatophyte Fungi Granuloma Histopathology Invasive infection Mycetoma 

Notes

Compliance with Ethical Standards

Conflict of interest

The authors report no conflicts of interest. The authors alone are responsible for the content and the writing of this paper.

Ethical Approval

This article does not describe any studies with human participants or animals performed by the authors.

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Copyright information

© Springer Nature B.V. 2019

Authors and Affiliations

  1. 1.Department of Dermatology, Faculty of MedicineBaşkent University Adana HospitalAdanaTurkey
  2. 2.Division of Mycology, Department of Microbiology, Faculty of MedicineUniversity of ÇukurovaAdanaTurkey
  3. 3.Westerdijk Fungal Biodiversity InstituteUtrechtThe Netherlands
  4. 4.Centre of Expertise in MycologyRadboud University Medical Centre/Canisius Wilhelmina HospitalNijmegenThe Netherlands

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