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Mycopathologia

, Volume 183, Issue 6, pp 973–977 | Cite as

Paracoccidioides brasiliensis Infection Mimicking Recurrent Hodgkin Lymphoma: A Case Report and Review of the Literature

  • Ayaz GhaniEmail author
  • Molly Weinberg
  • Nusrat Pathan
  • Ramapriya Vidhun
  • Steven Sieber
Original Paper
  • 95 Downloads

Abstract

Paracoccidioides infection is a rare entity in the USA. This dimorphic fungus is found in Central and South America and is thought to be acquired by inhalation through the soil. We report a case of Paracoccidioides brasiliensis infection presenting as a clavicular bone lesion, peripancreatic mass, and various skin lesions. A 35-year-old man with a history significant for Hodgkin lymphoma presented with a left clavicular mass that was suspected clinically and radiologically as recurrent Hodgkin lymphoma. He was not experiencing any associated symptoms and was undergoing chemotherapy treatment for his known Hodgkin disease. On CT imaging, the mass was seen as a lytic bone lesion with an overlying soft tissue mass. This was biopsied and histologically diagnosed as a Paracoccidioides brasiliensis infection with associated necrotizing granulomatous inflammation. Also found on the CT scan was an enlarging peripancreatic mass which on endoscopic biopsy had similar histologic findings. In conclusion, this report presents a rare case of Paracoccidioides brasiliensis infection mimicking recurrent Hodgkin lymphoma.

Keywords

Paracoccidioides Fungus Hodgkin lymphoma Granulomatous inflammation 

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Copyright information

© Springer Science+Business Media B.V., part of Springer Nature 2018

Authors and Affiliations

  • Ayaz Ghani
    • 1
    Email author
  • Molly Weinberg
    • 1
  • Nusrat Pathan
    • 1
  • Ramapriya Vidhun
    • 1
  • Steven Sieber
    • 1
  1. 1.Danbury Hospital, Western Connecticut Health NetworkDanburyUSA

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