Molecular Biology Reports

, Volume 45, Issue 5, pp 1445–1456 | Cite as

The application of gene marker-assisted selection and proteomics for the best meat quality criteria and body measurements in Qinchuan cattle breed

  • Mohamed E. Abd El-HackEmail author
  • Sameh A. Abdelnour
  • Ayman A. Swelum
  • Muhammad Arif


In the past few decades, enhancement of animal productivity has been gaining increasing attention among decisions-makers, politicians, mangers, and breeders, because of the increasing of world population and shortage of natural resources. The selection of high productivity animals is the main goal, through the application of genetic improvement programs. The use of molecular genetics has conferred significant breeding advantages over conventional breeding techniques. In this regard, many economic characteristics are controlled by a small number of multiple gene loci, each of which is responsible for trait diversity and hence they are referred to as quantitative trait loci (QTL). Single-nucleotide polymorphisms (SNPs), which have recently been discovered through DNA sequencing, are considered one of the most useful types of genetic marker. SNPs are found where different nucleotides occur at the same position in the DNA sequence. They are found in both coding and noncoding regions of the genome and are present at one SNP in every 1000 b. Strategies for the identification and application of markers are based on reference to examples of loci that can control various traits. Furthermore, markers for growth, body measurements, and meat quality traits are preferred, because they can be used to predict the performance of animals, via blood samples, in the first few days of animal life. Marker-assisted selection using SNPs, such asSIRT1, SIRT2, LPL, CRTC2, SIX4, UCPs, and ZBTB38as selection criteria of body measurements and meat traits in beef cattle, will be beneficial in selection and breeding programs. The proteomic is a novel marker and a new approache of biotechnology which increases the understanding of the biological processes, besides being a remarkable biomarker that interrelated to growth and meat quality traits. Proteomics is a vigorous tool as usage for deduces molecular processes between quality traits and muscle proteins, which are helpful in analyzing the mechanisms of biochemistry that influence quality. So they could be potential biomarker for some meat quality traits. Among them, Actin, Myosin, Heat shock proteins are used a novel approaches in the field of biotechnology to understand the proteomics changes. This review article highlights the novel findings on the potential use of MAS and proteomics as biomarker for the selection for meat quality and carcass traits in Qinchuan cattle breed.


Cattle Meat quality Gene marker-assisted Proteomics Selection 



Marker-assisted selection


Body length


Hip width


Withers height


Hip height


Rump length


Ultrasound backfat thickness


Chest circumference


Ultrasound loin muscle area


Pin bone width


Chest depth


Histone deacetylases


C-terminal binding proteins


Single-nucleotide polymorphism


Quantitative trait locus.



All authors thank their universities for their help in accomplishing this work.

Authors’ contributions

All authors contributed equally in writing this review article.

Compliance with ethical standards

Conflict of interest

Authors confirm that none of them have any competing interests in the manuscript.


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Copyright information

© Springer Nature B.V. 2018

Authors and Affiliations

  • Mohamed E. Abd El-Hack
    • 1
    Email author
  • Sameh A. Abdelnour
    • 2
  • Ayman A. Swelum
    • 3
    • 4
  • Muhammad Arif
    • 5
  1. 1.Department of Poultry, Faculty of AgricultureZagazig UniversityZagazigEgypt
  2. 2.Department of Animal Production, Faculty of AgricultureZagazig UniversityZagazigEgypt
  3. 3.Department of Animal Production, College of Food and Agriculture SciencesKing Saud UniversityRiyadhSaudi Arabia
  4. 4.Department of Theriogenology, Faculty of Veterinary MedicineZagazig UniversityZagazigEgypt
  5. 5.Department of Animal SciencesUniversity College of Agriculture, University of SargodhaSargodhaPakistan

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